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XRCC1 Antibody

XRCC1 Antibody is available 3 times from Njs poly labs

F49231-0.4ML | XRCC1 Antibody size: 0.4 ml | 447.86 USD

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F49231-0.08ML | XRCC1 Antibody size: 0.08 ml | 219.52 USD

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R30722 | XRCC1 Antibody size: 0.1mg | 429.11 USD

Catalog number R30722
Supplier NJS poly
Price 429.11 USD
Size 0.1mg
Concentration 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Species reactivity Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applications WB, IHC-P, ICC
Recommended dilutions Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
Notes The stated application concentrations are suggested starting amounts. Titration of the XRCC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description X-ray repair, complementing defective, in chinese hamster 1 is a DNA repair protein which complexes with DNA ligase III. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. The XRCC1 gene is mapped to 19q13.31. The protein interacts with DNA ligase III, polymerase beta and poly(ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. XRCC1 is phosphorylated in vivo and in vitro by CK2, and CK2 phosphorylation of ser518, thr519, and thr523 largely determines aprataxin binding to XRCC1 through its FHA domain.
Immunogen An amino acid sequence from the N-terminus of human XRCC1 (QDSTHCAENLLKADTYRKWR) was used as the immunogen for this XRCC1 antibody (100% mouse homology).
Storage After reconstitution, the XRCC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
1. Gene info
Identity 12828
Gene XRCC1
Long gene name X-ray repair cross complementing 1
Synonyms gene
  • RCC
Synonyms gene name
  • X-ray repair complementing defective repair in Chinese hamster cells 1
GenBank acession
  • M36089
Locus 19q13.2
Discovery year 2001-06-22
Entrez gene record 7515
Pubmed identfication
  • 2247054
RefSeq identity
  • NM_006297
Havana BLAST/BLAT OTTHUMG00000182699
Locus Specific Databases
  • LRG_784
MeSH Data
Name Blotting, Western
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Clonality Polyclonal (rabbit origin)
Category Antibody
Form Antigen affinity purified
Purity Antigen affinity
Host animal Rabbit (Oryctolagus cuniculus)
Recognised antigen XRCC1
Intented use This XRCC1 antibodyis to be used only for research purposes and not for diagnostics..
Conjugation Unconjugated
Uniprot # P18887
Clone Polyclonal antibody
Properties If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetXRCC1
Short name XRCC1 Antibody
Technique Antibody
Alternative name X-ray repair complementing defective repair in Chinese hamster cells 1 (Antibody to)
Alternative technique antibodies
Alternative to gene target X-ray repair complementing defective repair in Chinese hamster cells 1, RCC, XRCC1 and IDBG-55268 and ENSG00000073050 and 7515, protein binding, nuclei, Xrcc1 and IDBG-155000 and ENSMUSG00000051768 and 22594, XRCC1 and IDBG-639023 and ENSBTAG00000016268 and 616905
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XRCC1 Antibody size: 0.1mg - Gentaur.com
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