Kallikrein 1 Antibody

• Catalog number
  R31148
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Kallikrein 1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the Kallikrein 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Kallikrein 1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P15947
• Purity
  Antigen affinity
• Description
  Kallikrein 1, also called KLKR, is a protein that in humans is encoded by the KLK1 gene. It is a member of the peptidase S1 family, a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The gene contains 5 coding exons. KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
• Immunogen
  Mouse KLK1 partial recombinant protein (AA 25-261) was used as the immunogen for this Kallikrein 1 antibody.
• Storage
  After reconstitution, the Kallikrein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Kallikrein  
• Gene symbol
  KLK1, KLKP1, KLKB1
• Short name
  Anti-Kallikrein 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Kallikrein 1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6357
• Gene
  KLK1
• Long gene name
  kallikrein 1
• Synonyms gene name
  • kallikrein 1, renal/pancreas/salivary
• Synonyms
  • Klk6
• GenBank acession
  • L10038
• Locus
  19q13.33
• Discovery year
  1988-06-27
• Entrez gene record
  3816
• Pubmed identfication
  • 1684954
  • 16800724
  • 16800723
• RefSeq identity
  • NM_002257
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182876

Gene info

• Identity
  HGNC:21260
• Gene
  KLKP1
• Long gene name
  kallikrein pseudogene 1
• Synonyms
  • YKLK1
  • PsiKLK1
  • KLK31P
• Synonyms name
  • kallikrein 31 pseudogene
• GenBank acession
  • AY302756
• Locus
  19q13.33
• Discovery year
  2005-08-04
• Entrez gene record
  606293
• Pubmed identfication
  • 15498522
  • 16541416
  • 18196551
• RefSeq identity
  • NG_005220
• VEGA ID
  OTTHUMG00000183118

Gene info

• Identity
  HGNC:6371
• Gene
  KLKB1
• Long gene name
  kallikrein B1
• Synonyms gene
  • KLK3
• Synonyms gene name
  • kallikrein B, plasma (Fletcher factor) 1
• Synonyms name
  • Fletcher factor
• GenBank acession
  • M13143
• Locus
  4q35.2
• Discovery year
  1999-04-23
• Entrez gene record
  3818
• Pubmed identfication
  • 9535413
  • 3521732
• RefSeq identity
  • NM_000892
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000150347
• Locus Specific Databases
  • LRG_565

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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