A-1331852

• Catalog number
  B1948-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  3-(1-(adamantan-1-ylmethyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl) picolinic acid
• Description
  A-1331852 is a potent anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent useful in the treatment of cancer, immune and autoimmune diseases.
• CAS Number
  1430844-80-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₈H₃₈N₆O₃S
• Molecular Weight
  658.81
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent anti-apoptotic Bcl-xL protein inhibitor and apoptosis-inducing agent
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  71565985
• PubChem CID Link
• SMILES
  CC1=C(C=NN1CC23CC4CC(C2)CC(C4)C3)C5=C(N=C(C=C5)N6CCC7=CC=CC(=C7C6)C(=O)NC8=NC9=CC=CC=C9S8)C(=O)O
• InChi
  InChI=1S/C38H38N6O3S/c1-22-29(19-39-44(22)21-38-16-23-13-24(17-38)15-25(14-23)18-38)27-9-10-33(41-34(27)36(46)47)43-12-11-26-5-4-6-28(30(26)20-43)35(45)42-37-40-31-7-2-3-8-32(31)48-37/h2-10,19,23-25H,11-18,20-21H2,1H3,(H,46,47)(H,40,42,45)
• InChi Key
  QCQQONWEDCOTBV-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  A-1331852  
• Gene symbol
  HLA-A, IGHV5-10-1, CIDEA, RPA1, CDC37P1, OR1Q1, LINC01139, FABP4, GTF2E1
• Short name
  A-1331852
• Alternative name
  A-1331852

Gene info

• Identity
  HGNC:4931
• Gene
  HLA-A
• Long gene name
  major histocompatibility complex, class I, A
• GenBank acession
  • D32129
• Locus
  6p22.1
• Discovery year
  2001-06-22
• Entrez gene record
  3105
• Pubmed identfication
  • 8838351
• RefSeq identity
  • NM_002116
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000130501
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:5661
• Gene
  IGHV5-10-1
• Long gene name
  immunoglobulin heavy variable 5-10-1
• Synonyms gene
  • IGHV5-A
• Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
• Synonyms
  • IGHV5-a
• GenBank acession
  • X92227
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28386
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191143

Gene info

• Identity
  HGNC:1976
• Gene
  CIDEA
• Long gene name
  cell death inducing DFFA like effector a
• Synonyms gene name
  • cell death-inducing DFFA-like effector a
• Synonyms
  • CIDE-A
• GenBank acession
  • AF041378
• Locus
  18p11.21
• Discovery year
  1998-07-15
• Entrez gene record
  1149
• Pubmed identfication
  • 9564035
  • 18509062
• RefSeq identity
  • NM_001279
• VEGA ID
  OTTHUMG00000131691

Gene info

• Identity
  HGNC:10289
• Gene
  RPA1
• Long gene name
  replication protein A1
• Synonyms gene name
  • replication protein A1 (70kD)
  • replication protein A1, 70kDa
• Synonyms
  • REPA1
  • RPA70
  • HSSB
  • RF-A
  • RP-A
• GenBank acession
  • M63488
• Locus
  17p13.3
• Discovery year
  1993-12-14
• Entrez gene record
  6117
• Pubmed identfication
  • 8454588
• RefSeq identity
  • NM_002945
• Classification
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000090579

Gene info

• Identity
  HGNC:34406
• Gene
  CDC37P1
• Long gene name
  cell division cycle 37 pseudogene 1
• Synonyms gene name
  • cell division cycle 37 homolog (S. cerevisiae) pseudogene 1
• Synonyms
  • A-761H5.2
• Locus
  16p11.2
• Discovery year
  2009-01-29
• Entrez gene record
  390688
• Pubmed identfication
  • 15616553
• RefSeq identity
  • NG_009463
• VEGA ID
  OTTHUMG00000175739

Gene info

• Identity
  HGNC:8223
• Gene
  OR1Q1
• Long gene name
  olfactory receptor family 1 subfamily Q member 1
• Synonyms gene
  • OR1Q2
  • OR1Q3
• Synonyms gene name
  • olfactory receptor, family 1, subfamily Q, member 1
• Synonyms
  • OST226
  • OR9-A
  • HSTPCR106
  • OST226OR9-A
  • TPCR106
• Locus
  9q33.2
• Discovery year
  1999-12-09
• Entrez gene record
  158131
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000020615

Gene info

• Identity
  HGNC:27924
• Gene
  LINC01139
• Long gene name
  long intergenic non-protein coding RNA 1139
• Synonyms
  • LINK-A
  • TCONS_00000027
• Synonyms name
  • long intergenic non-coding RNA for kinase activation
• Locus
  1q43
• Discovery year
  2013-12-03
• Entrez gene record
  339535
• Pubmed identfication
  • 28218907
  • 26975198
• RefSeq identity
  • NR_015407
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000039532

Gene info

• Identity
  HGNC:3559
• Gene
  FABP4
• Long gene name
  fatty acid binding protein 4
• Synonyms
  • A-FABP
  • aP2
• Synonyms name
  • adipocyte fatty acid binding protein
• GenBank acession
  • J02874
• Locus
  8q21.13
• Discovery year
  1991-08-06
• Entrez gene record
  2167
• Pubmed identfication
  • 2481498
• RefSeq identity
  • NM_001442
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000164602

Gene info

• Identity
  HGNC:4650
• Gene
  GTF2E1
• Long gene name
  general transcription factor IIE subunit 1
• Synonyms gene name
  • general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD)
  • general transcription factor IIE, polypeptide 1, alpha 56kDa
• Synonyms
  • TFIIE-A
  • FE
• Synonyms name
  • TFIIE alpha subunit
• GenBank acession
  • S67859
• Locus
  3q13.33
• Discovery year
  1993-08-20
• Entrez gene record
  2960
• Pubmed identfication
  • 1454543
  • 8162052
• RefSeq identity
  • NM_005513
• Classification
  • General transcription factor IIE complex subunits
• VEGA ID
  OTTHUMG00000159667

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