anti-FoxA2 (HNF3beta) Antibody

• Catalog number
  79-710
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' . In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
• Gene names
  HNF3B, TCF3B, NMDAR1, HNF3B
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of total FoxA2 protein.
• Antigen
  FoxA2 (HNF3beta) antibody was made against a peptide sequence around aa.435~439 ( A-S-P-L-A) derived from Human FoxA2 (HNF3β).
• Immuno application
  Western Blot
• Antibody advice
  Western Blot: 1:500~1:1000
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human
• Omim nr
  194394143
• Ncbi nr
  NP_068556.2
• KDa
  50 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  3170
• GENE symbol
  FOXA2
• Antigene name
  forkhead box A2
• Source
  Homo sapiens
• Protein nr
  Q9Y261
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FoxA2   HNF3beta  
• Short name
  anti-FoxA2 (HNF3beta) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toFoxA2 (HNF3beta) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  forkhead box A2, HNF3B and TCF3B, FOXA2 and IDBG-59234 and ENSG00000125798 and 3170, transcription regulatory region DNA binding, nuclei, Foxa2 and IDBG-208945 and ENSMUSG00000037025 and 15376, FOXA2 and IDBG-648756 and ENSBTAG00000012407 and 503580

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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