DCLK2 Antibody

• Catalog number
  F47683-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  DCLK2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the DCLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This DCLK2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q8N568
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
• Immunogen
  A portion of amino acids 167-196 from the human protein was used as the immunogen for this DCLK2 antibody.
• Storage
  Aliquot the DCLK2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DCLK2  
• Gene symbol
  DCLK2
• Short name
  Anti-DCLK2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to DCLK2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:19002
• Gene
  DCLK2
• Long gene name
  doublecortin like kinase 2
• Synonyms gene
  • DCAMKL2
• Synonyms gene name
  • doublecortin and CaM kinase-like 2
  • doublecortin-like kinase 2
• Synonyms
  • MGC45428
  • DCDC3
  • DCDC3B
  • DCK2
• GenBank acession
  • BC032726
• Locus
  4q31.23-q31.3
• Discovery year
  2005-01-20
• Entrez gene record
  166614
• Pubmed identfication
  • 23385585
  • 26526391
• RefSeq identity
  • NM_001040260
• Classification
  • Doublecortin superfamily
• VEGA ID
  OTTHUMG00000161444

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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