PD-168393

  • Catalog number
    B2352-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    PD168393,N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-propenamide
  • Description
    PD-168393 is a cell-permeable, irreversible inhibitor of EGFR kinase activity (IC₅₀ = 0.70 nM). PD-168393 decreases the production of TNF-α and phosphorylation of ERK1/2 and p38 induced by LPS in cardiomyocytes.
  • CAS Number
    194423-15-9
  • Structure Available
    Yes
  • Molecular Formula
    C₁₇H₁₃BrN₄O
  • Molecular Weight
    369.2
  • Cell Permeable
    1
  • Purity
    ≥98% by HPLC
  • Solubilities
    >25 mg/ml (DMSO) in 0
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A potent, EGFR kinase inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD02179207
  • PubChem CID
    4708
  • SMILES
    C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br
  • InChi
    InChI=1S/C17H13BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h2-10H,1H2,(H,21,23)(H,19,20,22)
  • InChi Key
    HTUBKQUPEREOGA-UHFFFAOYSA-N
  • MSDS Available
    1
  • Gene target
  • Gene symbol
    ENPP2, PDCD1, ENPP3, PDCD1LG2, CD274, VSIR
  • Short name
    PD-168393
  • Alternative name
    PD-168393
Gene info
Gene info
Gene info
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