anti-SIN3B Antibody

  • Catalog number
    26-549
  • Price
    Please ask
  • Size
    50 ug
  • Gene info
    SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
  • Gene names
    SIN3B, KIAA0700
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibody is purified by peptide affinity chromatography method.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Antigen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIN3B.
  • Immuno application
    ELISA, Western Blot
  • Antibody advice
    SIN3B antibody can be used for detection of SIN3B by ELISA at 1:312500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
  • Suspention pH azide
    Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
  • Keep at
    For short periods of storage (days) store at 4 grades C. For longer periods of storage, store SIN3B antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
  • Works with
    Human, Mouse
  • Omim nr
    52138513
  • Ncbi nr
    NP_056075
  • KDa
    133 kDa
  • Vial with antibody
    Lyophilized
  • Quantity per ml
    1 mg/ml
  • NCBI GENE nr
    23309
  • GENE symbol
    SIN3B
  • Antigene name
    SIN3 transcription regulator family member B
  • Source
    Homo sapiens
  • Protein nr
    O75182
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    SIN3B  
  • Gene symbol
    SIN3B
  • Short name
    anti-SIN3B Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toSIN3B (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    SIN3 transcription regulator family member B
  • Synonyms gene name
    • SIN3 homolog B, transcription regulator (yeast)
    • SIN3 transcription regulator homolog B (yeast)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2002-10-09
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • EMSY complex
    • SIN3 histone deacetylase complex subunits
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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