anti-APOBEC3B Antibody

• Catalog number
  7725
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  The Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytosine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates (1). Similar to TRIM5? which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection (2,3). APOBEC3B has also been shown to be upregulated in several cancers; it is thought that APOBEC3B-catalyzed genomic uracil lesions are responsible for a large proportion of mutations in multiple distinct cancers (4).
• Gene names
  APOBEC3B Antibody: A3B, ARP4, ARCD3, PHRBNL, APOBEC1L, bK150C2.2, DJ742C19.2Phorbolin-1-related protein, A3B
• Antibodie s label
  unlabelled serum
• Purity
  APOBEC3B antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  APOBEC3B antibody is human, mouse and rat reactive . At least three isoforms of APOBEC3B are known to exist; this antibody will detect all three. APOBEC3B antibody may cross-react with APOBEC3D.
• Antigen
  APOBEC3B antibody was made against a 14 amino acid peptide near the amino terminus of human APOBEC3B.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  APOBEC3B antibody can be used for detection of APOBEC3B by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry at 5 ug/mL. For Immunoflorescence start at 20 ug/mL.
• Suspention pH azide
  APOBEC3B Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  APOBEC3B antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  393715117
• Ncbi nr
  NP_004891
• KDa
  Predicted: 42 kDa Observed: 48 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9582
• GENE symbol
  APOBEC3B
• Antigene name
  apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
• Source
  homo sapiens
• Protein nr
  Q9UH17
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  APOBEC3B  
• Gene symbol
  APOBEC3B-AS1, APOBEC3B
• Short name
  anti-APOBEC3B Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAPOBEC3B (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:43836
• Gene
  APOBEC3B-AS1
• Long gene name
  APOBEC3B antisense RNA 1
• Synonyms gene name
  • APOBEC3B antisense RNA 1 (non-protein coding)
• GenBank acession
  • CX754295
• Locus
  22q13.1
• Discovery year
  2012-03-23
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000151083

Gene info

• Identity
  HGNC:17352
• Gene
  APOBEC3B
• Long gene name
  apolipoprotein B mRNA editing enzyme catalytic subunit 3B
• Synonyms gene name
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
• Synonyms
  • PHRBNL
  • FLJ21201
• Synonyms name
  • phorbolin 3
• GenBank acession
  • AK024854
• Locus
  22q13.1
• Discovery year
  2001-12-12
• Entrez gene record
  9582
• Pubmed identfication
  • 11863358
  • 10469298
• RefSeq identity
  • NM_004900
• Classification
  • Apolipoprotein B mRNA editing enzyme catalytic subunits
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000151085

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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