Mouse Anti-Human KCNQ2 Monoclonal IgG1, Clone S26A-23
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Catalog numberSMC-308D-BI
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PricePlease ask
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Size100 µg
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CloneS26A-23
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ImmunogenFusion protein amino acids 1-59 of human KCNQ2
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Antibody s full descriptionMouse Anti-Human KCNQ2 Monoclonal IgG1 Antibody, Clone: S26A-23: Biotin
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Antibody s categoryMonoclonal Antibodies
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Antibody s other nameBFNC Antibody, EBN1 Antibody, ENB1 Antibody, HNSPC Antibody, KCNA11 Antibody, KQT like 2 Antibody, KV7.2 Antibody, KVEBN1. KvLQT2 Antibody, voltage gated potassium channel subunit Kv7.2 Antibody
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Raised inMouse
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Antibody s targetKCNQ2
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Primary research fieldsNeuroscience, Ion Channels, Potassium Channels, Voltage-Gated Potassium Channels, Cancer
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BrandnameNone
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Antibodies applicationsWB, IHC, ICC/IF, IP, AM
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Antibody s reactivityHuman, Mouse, Rat, Hamster
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Antibody s dilutionsWB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
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PurityProtein G Purified
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Antibody buffer for storagePBS pH7.4, 50% glycerol, 0.09% sodium azide
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Antibody s concentration1 mg/ml
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Antibody s specificityDetects ~95kDa.
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Storage recommendations-20ºC
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Shipping recommendationsBlue Ice or 4ºC
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Antibody certificate of analysis1 µg/ml of SMC-308 was sufficient for detection of KCNQ2 in 10 µg of COS-1 cell lysate transiently expressing KCNQ2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Antibody in cellMembrane
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Tissue specificitySee included datasheet or contact our support service
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Scientific contextKv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2. It is associated with benign familial neonatal convulsions (1).
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Bibliography1. Wuttke T.V., et al. (2008) J Physiol. 586(2): 545-555.
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Released date30-Jul-2009
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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NCBI numberNP_004509.2
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Gene number3785
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Protein numberO43526
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Antibody s datasheetContact our support service
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Representative figure link
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Representative figure legendImmunohistochemistry analysis using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Tissue: frozen brain section. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Western Blot analysis of Human, hamster HEK and CHO cell lysates showing detection of KCNQ2 protein using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. KCNQ2 overexpressed. Immunohistochemistry analysis using Mouse Anti-KCNQ2 Monoclonal Antibody, Clone S26A-23 (SMC-308). Tissue: hippocampus. Species: Human. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-KCNQ2 Monoclonal Antibody (SMC-308) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Mouse Anti-KCNQ2 antibody [S26A-23] used in Immunohistochemistry (IHC) on Mouse frozen brain section (SMC-308) Mouse Anti-KCNQ2 Antibody [S26A-23] used in Western Blot (WB) on Human, hamster HEK and CHO cell lysates (SMC-308) Mouse Anti-KCNQ2 Antibody [S26A-23] used in Immunohistochemistry (IHC) on Human hippocampus (SMC-308)
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilityIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Latin nameMus musculus
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Gene target
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Gene symbolKCNQ2-AS1, IGHV3-23, IGKV2D-23, SNORD116-23, SNORD114-23, SNORD115-23, IGKV2-23, ERVW-23, IGLV2-23, ERVK-23
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Short nameMouse Anti- KCNQ2 Monoclonal IgG1, Clone S26A-23
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Techniqueanti-Human, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, Monoclonals or monoclonal antibodies, mouses
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Hostmouse
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IsotypeIgG1, IgG1
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LabelBiotin
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SpeciesHuman, Humans, Mouses
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Alternative nameMouse Antibody toHuman KCNQ2 monoclonal IgG1, clonality S26A-23
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Alternative techniquemurine, antibodies
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Clone nameS26A-23
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Gene info
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Identity
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Gene
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Long gene nameKCNQ2 antisense RNA 1
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Locus
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Discovery year2019-08-15
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-23
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 2D-23 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 2D-23
- immunoglobulin kappa variable 2D-23 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-23
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-23
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-23
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 2-23 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 2-23
- immunoglobulin kappa variable 2-23 pseudogene
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin kappa locus at 2p11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameendogenous retrovirus group W member 23
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Synonyms gene name
- endogenous retrovirus group W, member 23
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GenBank acession
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Locus
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Discovery year2013-10-21
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin lambda variable 2-23
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GenBank acession
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Locus
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Discovery year2000-05-08
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin lambda locus at 22q11.2
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameendogenous retrovirus group K member 23
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Synonyms gene name
- endogenous retrovirus group K, member 23
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Synonyms
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GenBank acession
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Locus
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Discovery year2011-05-05
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Pubmed identfication
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data