Annexin VIII Antibody

• Catalog number
  3637R-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  Annexin A8
• Target Alternative Name
  ANXA7 , ANX7 , SNX , Annexin A7
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 316 of human Annexin VIII
• Accession
  P13928
• Gene Id
  653145
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) protein A purified rabbit anti-Annexin VIII polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Application
  Western blot, Immunohistochemistry
• Positive Control
  Western Blot: Jurkat cell lysate. IHC: Placenta tissue
• Application And Usages
  Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml) . However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control. The antibody detects 36 kDa annexin VIII of human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate
• Description
  The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This Annexin V calcium dependent phospholipid binding protein will be downstream of BCL2 pathway and at caspase apoptotic level. Biovision has more cell death kits and antibodies.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Annexin   VIII  
• Gene symbol
  COX8A, G3BP1, MARCHF8
• Short name
  Annexin VIII Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Annexin VIII (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2294
• Gene
  COX8A
• Long gene name
  cytochrome c oxidase subunit 8A
• Synonyms gene
  • COX8
• Synonyms gene name
  • cytochrome c oxidase subunit VIII
  • cytochrome c oxidase subunit VIIIA (ubiquitous)
• Synonyms
  • COX8-2
  • COX8L
  • VIII-L
  • COX
  • VIII
• GenBank acession
  • J04823
• Locus
  11q13.1
• Discovery year
  1989-06-30
• Entrez gene record
  1351
• Pubmed identfication
  • 2543673
  • 2847943
  • 26685157
• RefSeq identity
  • NM_004074
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000167785

Gene info

• Identity
  HGNC:30292
• Gene
  G3BP1
• Long gene name
  G3BP stress granule assembly factor 1
• Synonyms gene name
  • GTPase activating protein (SH3 domain) binding protein 1
• Synonyms
  • HDH-VIII
  • G3BP
• Synonyms name
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • DNA helicase VIII
• GenBank acession
  • BC006997
• Locus
  5q33.1
• Discovery year
  2006-10-25
• Entrez gene record
  10146
• Pubmed identfication
  • 8649363
  • 9889278
  • 25229650
• RefSeq identity
  • NM_005754
• Classification
  • RNA binding motif containing
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000130123

Gene info

• Identity
  HGNC:23356
• Gene
  MARCHF8
• Long gene name
  membrane associated ring-CH-type finger 8
• Synonyms gene
  • MIR
  • MARCH8
• Synonyms gene name
  • c-mir, cellular modulator of immune recognition
  • membrane-associated ring finger (C3HC4) 8
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
• Synonyms
  • c-MIR
  • CMIR
  • MARCH-VIII
  • RNF178
• GenBank acession
  • AL833316
• Locus
  10q11.21-q11.22
• Discovery year
  2003-11-12
• Entrez gene record
  220972
• Pubmed identfication
  • 12582153
  • 14722266
• RefSeq identity
  • NM_145021
• Classification
  • Ring finger proteins
  • Membrane associated ring-CH-type fingers
• VEGA ID
  OTTHUMG00000019345

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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