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Anti-CPA3/MC-CPA (Polyclonal), ALEXA Fluor 594

Anti-CPA3/MC-CPA (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-12338R-A594 | Anti-CPA3/MC-CPA (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 568.71 USD

Catalog number GENTObs-12338R-A594
Price 568.71 USD
Size 100 microliters
1. Gene info
Identity 2296
Gene CPA1
Long gene name carboxypeptidase A1
Synonyms gene
  • CPA
Synonyms gene name
  • carboxypeptidase A1 (pancreatic)
Synonyms name
  • pancreatic carboxypeptidase A
Locus 7q32.2
Discovery year 1986-01-01
Entrez gene record 1357
RefSeq identity
  • NM_001868
Classification
  • M14 carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000157826
2. Gene info
Identity 2298
Gene CPA3
Long gene name carboxypeptidase A3
Synonyms gene name
  • carboxypeptidase A3 (mast cell)
Synonyms name
  • mast cell carboxypeptidase A
  • tissue carboxypeptidase A
Locus 3q24
Discovery year 1990-06-13
Entrez gene record 1359
RefSeq identity
  • NM_001870
Classification
  • M14 carboxypeptidases
Havana BLAST/BLAT OTTHUMG00000159526
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide CPA3/MC-CPA
Specificity This antibody reacts specifically with CPA3/MC-CPA
Modification No modification has been applied to this antibody
Modification site None
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations N/A
Antigen Source KLH conjugated synthetic peptide derived from human CPA3/MC-CPA
Gene ID 1359
Swiss Prot N/A
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms carboxypeptidase A; Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; Mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA.
Also known as CPA3/MC-CPA Polyclonal Antibody
Other name Anti-CPA3/MC-CPA Polyclonal
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetCPA3/MC-CPA
Short name Anti-CPA3/MC-CPA
Technique Polyclonal, anti
Isotype Immunoglobulin G (IgG)
Label ALEXA FLUOR 594
Alternative name CPA3/MC-CPA Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative technique polyclonals
Alternative to gene target carboxypeptidase A3 (mast cell), MC-CPA, CPA3 and IDBG-60396 and ENSG00000163751 and 1359, zinc ion binding, Extracellular, Cpa3 and IDBG-133537 and ENSMUSG00000001865 and 12873, CPA3 and IDBG-637892 and ENSBTAG00000015008 and 528454
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Anti-CPA3/MC-CPA | Technique alternative | 01011207267
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