Beta Arrestin 2 Antibody
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Catalog numberR30943
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PricePlease ask
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Size0.1mg
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CategoryAntibody
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Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
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FormAntigen affinity purified
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ConjugationUnconjugated
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ClonePolyclonal antibody
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Recognised antigenBeta Arrestin 2
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Host animalRabbit (Oryctolagus cuniculus)
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ClonalityPolyclonal (rabbit origin)
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Species reactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
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Tested applicationsWB, IHC-P
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Recommended dilutionsWestern blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml
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NotesThe stated application concentrations are suggested starting amounts. Titration of the Beta Arrestin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Intented useThis Beta Arrestin 2 antibodyis to be used only for research purposes and not for diagnostics..
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UniprotP32121
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PurityAntigen affinity
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DescriptionBeta Arrestin 2 is an intracellular protein that in humans is encoded by the ARRB2 gene. Members of the arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals, as well as having signalling roles in their own right. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptorfunction in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Beta-arrestins were originally discovered in the context of heterotrimeric G protein-coupled receptor desensitization, but they also function in internalization and signaling of these receptors.
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ImmunogenAn amino acid sequence from the C-terminus of human ARRB2 (RLKGMKDDDYDDQLC) was used as the immunogen for this Beta Arrestin 2 antibody.
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StorageAfter reconstitution, the Beta Arrestin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
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PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolARRB2, ARRB1
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Short nameAnti-Beta Arrestin 2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAntibodies to Beta Arrestin 2
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namearrestin beta 2
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Synonyms gene
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Synonyms gene name
- arrestin, beta 2
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Synonyms
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Synonyms name
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Locus
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Discovery year1994-01-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Classical arrestins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namearrestin beta 1
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Synonyms gene
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Synonyms gene name
- arrestin, beta 1
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-01-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Classical arrestins
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data