Recombinant Mouse CD83 / HB15 Protein (Fc tag) 100µg
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Catalog number
PKSM040542-100µg
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Price
Please ask
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Size
100µg
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Activity
NA
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Synonym
MGC130312, MGC130313
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Sequence
Met 1-Arg 133
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Fusion tag
C-Fc
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Accession
O88324
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 90 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
39.2 kDa
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AP Mol Mass
50-55 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhaunce the rate of tumor growth and inhibit the T cell growth.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CD83
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Short name
Recombinant Mouse CD83 / HB15 Protein (Fc tag) 100µg
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Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
mouse
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Label
Fc Tag
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse CD83 molecule / HB15 Protein (fragment c detection labelled) 100µg
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Alternative technique
rec, murine
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Alternative to gene target
CD83 molecule, BL11 and HB15, CD83 and IDBG-62750 and ENSG00000112149 and 9308, protein binding, Cell surfaces, Cd83 and IDBG-147707 and ENSMUSG00000015396 and 12522, CD83 and IDBG-636028 and ENSBTAG00000031430 and 617034
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Gene info
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Identity
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Gene
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Long gene name
CD83 molecule
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Synonyms gene name
- CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
- CD83 molecule
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Synonyms
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GenBank acession
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Locus
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Discovery year
1999-03-26
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- V-set domain containing
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VEGA ID
Product images
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