NFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 647
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Catalog numberbs-0074R-A647
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PricePlease ask
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Size100ul
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Long nameNFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 647 Conjugated
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Also known asAnti-NFkB Inducing Kinase NIK PAb ALEXA FLUOR 647
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 647
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenNFkB Inducing Kinase NIK
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SpecificityThis is a highly specific antibody against NFkB Inducing Kinase NIK.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range900-947/947
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Subcellular locationCytoplasm
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NIK
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Gene ID Number9020
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Swiss ProtQ99558
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenLymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P1, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission650nm/665nm
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SynonymsHS; NIK; HSNIK; FTDCR1B; Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; Serine/threonine-protein kinase NIK; MAP3K14
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-NFkB Inducing Kinase NIK exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 647
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GeneNF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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French translationanticorps
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Gene target
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Gene symbolMAP4K4, MAP3K14
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Short nameAnti-NFkB Inducing Kinase NIK
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 647
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Alternative nameNFkB Inducing Kinase NIK Antibody, ALEXA FLUOR 647
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase kinase 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinase kinases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemitogen-activated protein kinase kinase kinase 14
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-08-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitogen-activated protein kinase kinase kinases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data