Modification No modification has been applied to this antibody
Clonality Polyclonal Antibody
Other name Anti-C9b/C9 Polyclonal
Host organism Rabbit (Oryctolagus cuniculus)
Background information C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
Also known as C9b/C9 Polyclonal Antibody
Swiss Prot N/A
Specificity This antibody reacts specifically with C9b/C9
Modification site None
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Conjugated with ALEXA FLUOR® 594
Gene ID 735
Clone Polyclonal Antibodies
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Synonyms CO9_HUMAN; Complement component C9; Complementcomponent C9b.
Subcellular locations N/A
Concentration 1ug per 1ul
Purification method Purified by Protein A.
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Type Conjugated Primary Antibody
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Excitation emission 590nm/617nm
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Target Protein/Peptide Complement component C9b
Antigen Source KLH conjugated synthetic peptide derived from human Complement component C9b
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Short name Anti-C9b/C9 (Polyclonal)
Technique Polyclonal, anti
Label ALEXA FLUOR 594
Alternative name antibody to-C9b/complement component 9 (polyclonal), ALEXA Fluor 594
Alternative technique polyclonals
Alternative to gene target complement component 9, ARMD15 and C9D, C9 and IDBG-17892 and ENSG00000113600 and 735, protein binding, Extracellular, C9 and IDBG-128081 and ENSMUSG00000022149 and 12279, C9 and IDBG-629942 and ENSBTAG00000016149 and 526766