Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking, Polyclonal Antibody

• Catalog number
  X2404P
• Price
  Please ask
• Size
  100µg

• Host Source
  Rabbit
• Clone Name
  NA
• Product Category
  Lipid Mediators
• Species Reactivity
  Human
• Application
  Western Blot, Functional epitope reported to block PCSK9-LDLR interaction. ELISA
• Immunogen
  Synthetic peptide derived from the human PCSK9 protein reported to block PCSK9-LDLR interaction.
• Purification Method
  Ammonium Sulfate Precipitation
• Shipping Conditions
  Ship at ambient temperature, freeze upon arrival
• Storage conditions
  Proprotein convertase subtilisin/kexin type 9 (PCSK9), LDLR-binding epitope blocking, Polyclonal Antibody should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
• Datasheet link
• Properties
  If you buy Antibodies supplied by Exalpha they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  You can block the antibody by the specific target amino acid sequence of peptide.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Proprotein   convertase   subtilisin/kexin   PCSK9   LDLR-binding   epitope  
• Gene symbol
  LDLR, LDLR-AS1, PCSK9
• Short name
  Proprotein convertase subtilisin/kexin 9 (PCSK9), LDLR-binding epitope blocking, Polyclonal Antibody
• Technique
  Polyclonal, Antibody, Blocking, antibodies against human proteins, antibodies for, blocking peptides, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  IgG
• Alternative name
  Proprotein convertase subtilisin/kexin classification 9 (proprotein convertase subtilisin/kexin classification 9), low density lipoprotein receptor-binding epitope inhibiting, polyclonal (antibody to-)
• Alternative technique
  polyclonals, control, antibodies
• Alternative to gene target
  low density lipoprotein receptor, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, very-low-density lipoprotein particle receptor activity, Cell surfaces, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276

Gene info

• Identity
  HGNC:6547
• Gene
  LDLR
• Long gene name
  low density lipoprotein receptor
• Synonyms
  • LDLCQ2
• Synonyms name
  • familial hypercholesterolemia
• GenBank acession
  • AY114155
• Locus
  19p13.2
• Discovery year
  1986-01-01
• Entrez gene record
  3949
• Classification
  • Low density lipoprotein receptors
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000171935
• Locus Specific Databases
  • UCL LDLR-LOVD, British Heart Foundation variant database
  • UMD Locus Specific Databases
  • LRG_274

Gene info

• Identity
  HGNC:54407
• Gene
  LDLR-AS1
• Long gene name
  LDLR antisense RNA 1
• Synonyms
  • BM450697
• Locus
  19p13.2
• Discovery year
  2019-08-08
• Entrez gene record
  115271120
• Pubmed identfication
  • 31279228
• RefSeq identity
  • NR_163945
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:20001
• Gene
  PCSK9
• Long gene name
  proprotein convertase subtilisin/kexin type 9
• Synonyms gene
  • HCHOLA3
• Synonyms gene name
  • hypercholesterolemia, autosomal dominant 3
• Synonyms
  • NARC-1
  • FH3
• GenBank acession
  • AX207686
• Locus
  1p32.3
• Discovery year
  2003-05-13
• Entrez gene record
  255738
• Pubmed identfication
  • 12552133
  • 12730697
• RefSeq identity
  • NM_174936
• Classification
  • Proprotein convertase subtilisin/kexin family
• VEGA ID
  OTTHUMG00000008136
• Locus Specific Databases
  • British Heart Foundation
  • LRG_275

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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