anti-GAT-1 Antibody
-
Catalog number50-215
-
PricePlease ask
-
Size0.1 mL
-
-
Gene infoGamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).
-
Gene namesGat1, Gabt1, Gat-1, Gat1, Solute carrier family 6 member 1, GAT-1
-
Antibodie s labelunlabelled serum
-
PurityAffinity Purified
-
Ab raised inRabbit
-
TypePolyclonal
-
AntigenPeptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
-
Immuno applicationWestern Blot, immuno-histo-chemistry
-
Antibody adviceThe antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will also react with mouse tissue based on the fact that this species has 100% homology with the amino acid sequence used as antigen.
-
Suspention pH azide100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
-
Keep atGAT-1 antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
-
Works withMouse, Rat
-
Omim nr128609
-
Ncbi nrP23978
-
KDa67
-
Vial with antibodyin solution
-
NCBI GENE nr79212
-
GENE symbolSlc6a1
-
Antigene namesolute carrier family 6 (neurotransmitter transporter), member 1
-
SourceRattus norvegicus
-
Protein nrP23978
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolTRI-GAT1-1, TRI-GAT1-2, TRI-GAT1-3, GLYAT, SLC6A1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
-
Short nameanti-GAT-1 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toGAT-1 (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-Ile (anticodon GAT) 1-1
-
Synonyms gene
-
Synonyms gene name
- transfer RNA isoleucine 7 (anticodon GAU)
- transfer RNA-Ile (GAT) 1-1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-08-29
-
Entrez gene record
-
Classification
- Cytoplasmic transfer RNAs
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-Ile (anticodon GAT) 1-2
-
Synonyms gene
-
Synonyms gene name
- transfer RNA isoleucine 3 (anticodon GAU)
- transfer RNA-Ile (GAT) 1-2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-08-29
-
Entrez gene record
-
Classification
- Cytoplasmic transfer RNAs
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-Ile (anticodon GAT) 1-3
-
Synonyms gene
-
Synonyms gene name
- transfer RNA isoleucine 26 (anticodon GAU)
- transfer RNA-Ile (GAT) 1-3
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2008-08-29
-
Entrez gene record
-
Classification
- Cytoplasmic transfer RNAs
Gene info
-
Identity
-
Gene
-
Long gene nameglycine-N-acyltransferase
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2001-05-04
-
Entrez gene record
-
RefSeq identity
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namesolute carrier family 6 member 1
-
Synonyms gene name
- solute carrier family 6 (neurotransmitter transporter, GABA), member 1
- solute carrier family 6 (neurotransmitter transporter), member 1
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1994-02-16
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Solute carriers
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
-
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-17
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1/206 family
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 8-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 7-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
-
Synonyms gene
-
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Immunoglobulin kappa (IGK) orphons
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data