3,3'-Diindolylmethane

• Catalog number
  2150-1000
• Price
  Please ask
• Size
  1 g

• Alternative_name
  3,3’-Methylenediindole; DIM
• Description
  Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.
• CAS Number
  1968-05-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₄N₂
• Molecular Weight
  246.31
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of cancer stem cells
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD00195766
• PubChem CID
  3071
• PubChem CID Link
• SMILES
  C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43
• InChi
  InChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
• InChi Key
  VFTRKSBEFQDZKX-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Diindolylmethane  
• Short name
  3 3'-Diindolylmethane
• Alternative name
  3,3'-Diindolylmethane

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