MISRII/AMHR2 Antibody

• Catalog number
  bs-12414R
• Price
  Please ask
• Size
  0.1ml

• Long name
  MISRII/AMHR2 Primary Polyclonal Antibody
• Also known as
  MISRII/AMHR2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  MISRII/AMHR2
• Specificity
  This is a highly specific antibody against MISRII/AMHR2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MISRII/AMHR2
• Gene ID number
  269
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AMH type II receptor; AMHR2; AMHR2_HUMAN; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; MGC141312; MIS type II receptor; MISRII; MRII; Muellerian hormone type 2 receptor; Muellerian hormone type II receptor; Mullerian hormone receptor type II.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MISRII/AMHR2  
• Gene symbol
  AMHR2
• Short name
  Anti-MISRII/AMHR2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  MISRII/AMHR2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  anti-Mullerian hormone receptor, type II, AMHR and MISR2 and MISRII and MRII, AMHR2 and IDBG-36672 and ENSG00000135409 and 269, transforming growth factor beta receptor activity, Plasma membranes, Amhr2 and IDBG-188637 and ENSMUSG00000023047 and 110542, AMHR2 and IDBG-631327 and ENSBTAG00000018524 and

Gene info

• Identity
  HGNC:465
• Gene
  AMHR2
• Long gene name
  anti-Mullerian hormone receptor type 2
• Synonyms gene name
  • anti-Mullerian hormone receptor type II
• Synonyms
  • MISR2
  • MISRII
• Synonyms name
  • Muellerian inhibiting substance type II receptor
• GenBank acession
  • AF172932
• Locus
  12q13.13
• Discovery year
  1997-07-22
• Entrez gene record
  269
• Pubmed identfication
  • 7493017
• RefSeq identity
  • NM_020547
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000170048

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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