Caspase-10 Substrate AEVD-pNA
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Catalog number
1114-1000
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Price
Please ask
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Size
1000 assays
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Alternative_name
Ac-AEVD-pNA, Caspase-10 Substrate, Colorimetric
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Description
Ready-to-use colorimetric substrate for caspases that recognize the amino acid sequence AEVD. Caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleaved from the peptide substrate AEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economical alternative for researchers who perform large volume of caspase assays.
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Structure Available
No
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Peptide sequence
Ac-Ala-Glu-Val-Asp-pNA
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Salt Form
No
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Molecular Formula
C₂₅H₃₄N₆O₁₁
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Molecular Weight
594.7
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Cell Permeable
No
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Purity
>99% by HPLC
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Handling
Protect from light and moisture
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Tag Line
A caspase-10 substrate
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
12 months
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PubChem CID
44135310
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SMILES
CC(C)C(C(=O)NC(CC(=O)O)C(=O)NC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C
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InChi
InChI=1S/C25H34N6O11/c1-12(2)21(30-23(38)17(9-10-19(33)34)28-22(37)13(3)26-14(4)32)25(40)29-18(11-20(35)36)24(39)27-15-5-7-16(8-6-15)31(41)42/h5-8,12-13,17-18,21H,9-11H2,1-4H3,(H,26,32)(H,27,39)(H,28,37)(H,29, 40)(H,30,38)(H,33,34)(H,35,36)
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InChi Key
BKZWKAJKSQIGBP-UHFFFAOYSA-N
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MSDS Available
Yes
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Additional description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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