FKBP6 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-7126R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  FKBP6 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-FKBP6 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FKBP6
• Specificity
  This is a highly specific antibody against FKBP6.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP6
• Gene ID Number
  8468
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  FKBP6 is a 327 amino acid protein that, like other PPIases, accelerate the folding of proteins. As a component in synaptonemal complexes, FKBP6 is involved in homologous chromosomes pairing and male infertility in mice. There has been some suggestion that FKBP6 may play a role in modifying the susceptibility to idiopathic spermatogenic impairment in humans. Ubiquitously expressed in all tissues, FKBP6 is present at highest levels in testis, liver, kidney, skeletal muscle and heart. The gene encoding FKBP6 maps within a region of human chromosome 7 that has been implicated in Williams-Beuren syndrome, a rare developmental disorder involving abnormalities of the cardiovascular and musculoskeletal systems. Hemizygous deletion of FKBP6 may contribute to hypercalcemia and growth delay in Williams-Beuren syndrome.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; EC 5.2.1.8; FK506 binding protein 6; FK506-binding protein 6; FKBP 36; FKBP-36; FKBP-6; FKBP36; fkbp6; FKBP6_HUMAN; Immunophilin FKBP36; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP6; PPIase; PPIase FKBP6; Rotamase.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-FKBP6 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  FKBP6  
• Gene symbol
  FKBP6, FKBP10
• Short name
  Anti-FKBP6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  FKBP6 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  FK506 binding protein 6, 36kDa, FKBP36, FKBP6 and IDBG-19838 and ENSG00000077800 and 8468, Hsp90 protein binding, Cytoplasm, Fkbp6 and IDBG-203707 and ENSMUSG00000040013 and 94244, FKBP6 and IDBG-640067 and ENSBTAG00000002253 and 537921

Gene info

• Identity
  HGNC:3722
• Gene
  FKBP6
• Long gene name
  FKBP prolyl isomerase family member 6 (inactive)
• Synonyms gene name
  • FK506-binding protein 6 (36kD)
  • FK506 binding protein 6, 36kDa
• Synonyms
  • PPIase
  • FKBP36
• Synonyms name
  • FK506 binding protein 6 (36kD)
  • peptidylprolyl cis-trans isomerase
  • rotamase
  • immunophilin FKBP36
• GenBank acession
  • AF038847
• Locus
  7q11.23
• Discovery year
  1998-12-09
• Entrez gene record
  8468
• Pubmed identfication
  • 9782077
  • 18529014
  • 19001379
• RefSeq identity
  • NM_003602
• Classification
  • FKBP prolyl isomerases
• VEGA ID
  OTTHUMG00000150520

Gene info

• Identity
  HGNC:18169
• Gene
  FKBP10
• Long gene name
  FKBP prolyl isomerase 10
• Synonyms gene name
  • FK506 binding protein 10 (65 kDa)
  • FK506 binding protein 10, 65 kDa
  • FK506 binding protein 10
• Synonyms
  • hFKBP65
  • FKBP65
  • FLJ22041
  • FKBP6
  • FLJ20683
  • FLJ23833
• GenBank acession
  • AB045981
• Locus
  17q21.2
• Discovery year
  2002-03-12
• Entrez gene record
  60681
• Pubmed identfication
  • 11071917
  • 18786928
• RefSeq identity
  • NM_021939
• Classification
  • EF-hand domain containing
  • FKBP prolyl isomerases
• VEGA ID
  OTTHUMG00000133497
• Locus Specific Databases
  • Osteogenesis Imperfecta Variant Database
  • LRG_12

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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