Rabbit Anti-Human PAK5 (pSer602) Polyclonal: RPE
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Catalog numberSPC-1045D-RPE
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PricePlease ask
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Size100 µl
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ImmunogenA phospho-specific peptide corresponding to residues surrounding Ser602 of human PAK5 (AA599-605)
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Antibody s targetHuman PAK5 (pSer602)
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Antibody s full descriptionRabbit Anti-Human PAK5 (pSer602) Polyclonal
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Antibody s categoryPolyclonal Antibodies
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Antibody s other namePAK 5 Antibody, PAK 7 Antibody, PAK-5 Antibody, PAK-7 Antibody, PAK5 Antibody, PAK7 Antibody, PAK7_HUMAN Antibody, Protein kinase PAK5 Antibody, Serine/threonine protein kinase PAK 7 Antibody, Serine/threonine-protein kinase PAK 7 Antibody, EC 2.7.11.1 Antibody, KIAA1264 Antibody, MGC26232 Antibody, p21 activated kinase 7 Antibody, p21 protein (Cdc42/Rac)-activated kinase 7 Antibody, p21(CDKN1A) activated kinase 7 Antibody, p21-activated kinase 5 Antibody, p21-activated kinase 7 Antibody
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Verified applicationsWB, AM
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Raised inRabbit
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Antibody s reactivityHuman
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Antibody s recommended dilutions for useWB (1:250); optimal dilutions for assays should be determined by the user.
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Antibody s purified fromPeptide Affinity Purified
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Recommended buffer for storagePBS pH7.4, 50% glycerol, 0.025% Thimerosal
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Antibody s concentrationSee included datasheet or contact our support service
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Antibody s specificityDetects 80.745 kDa.
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Storage recommendations-20°C
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Shipping recommendationsBlue Ice or 4°C
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Certificate of analysisA 1:250 dilution of SPC-1045 was sufficient for detection of PAK5 (pSer602) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Antibody in cellMitochondrion, Cytoplasm, Nucleus
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Tissue specificityHighly expressed in the brain.
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Scientific contextPAK7 is a serine/theonine protein kinase activated by Rac/cdc42 and thus involved in regulation of cytoskeleton, cell surival and proliferation through RAF1 signalling. It phosphosphorylates BAD and prevents apoptosis. It is also involved in microtuble stablization, neurite outgrowth and development. It can destablize F-acting networks and eliminate stress fibres and focal adhesions. Pak7 expression provides a survival and could contribute to oncogenesis in this way.
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BibliographyRefer to PubMed
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Released date29/Aug/2016
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NCBI numberNP_065074
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Gene number57144
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Protein numberQ9P286
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PubMed numberRefer to PubMed
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Tested applicationsTo be tested
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Tested reactivityTo be tested
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Antibody s datasheetContact our support service to receive datasheet or other technical documentation.
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Representative figure linkNo Data Available
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Warning informationNon-hazardous
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Country of productionCanada
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Total weight kg1.4
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Net weight g0.1
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Stock availabilitIn Stock
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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TestStressMark antibodies supplies antibodies that are for research of human proteins.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolRPE, PAK6, PAK5
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Short nameRabbit Anti- PAK5 (pSer602) Polyclonal: RPE
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Techniqueanti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeImmunoglobulin
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LabelRPE
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit Antibody toHuman PAK5 (pSer602) polyclonal: RPE
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Alternative techniquepolyclonals, rabbit-anti, antibodies
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Gene info
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Identity
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Gene
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Long gene nameribulose-5-phosphate-3-epimerase
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namep21 (RAC1) activated kinase 6
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Synonyms gene name
- p21(CDKN1A)-activated kinase 6
- p21 protein (Cdc42/Rac)-activated kinase 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-07-12
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namep21 (RAC1) activated kinase 5
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Synonyms gene
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Synonyms gene name
- p21(CDKN1A)-activated kinase 7
- p21 protein (Cdc42/Rac)-activated kinase 7
- p21 (RAC1) activated kinase 7
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-21
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data