Mouse Suppressor of cytokine signaling 1 (Socs1)

  • Catalog number
    CSB-EP022388MO-50ug
  • Price
    Please ask
  • Size
    50ug
  • Description
    Recombinant Mouse Suppressor of cytokine signaling 1(Socs1) expressed in E.coli
  • Specifications
    Uniprot ID: O35716; Host: Mus musculus (Mouse); Expression system: E.coli; Expression region: 1-212aa; Sequence information: Full Length; Tag: N-terminal 10xHis-tagged and C-terminal Myc-tagged; Purity: Greater than 85% as determined by SDS-PAGE.
  • Additional_information
    MW: 28.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
  • Storage_and_shipping
    Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
  • Notes
    For research use only.
  • Additional description
    Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • Gene target
  • Gene symbol
    SOCS1
  • Short name
    Mouse Suppressor of cytokine signaling 1 (Socs1)
  • Technique
    Mouse, mouses
  • Host
    mouse
  • Species
    Mouse, Mouses
  • Alternative name
    Mouse Suppressor on cytokine signaling 1 (suppressor on cytokine signaling 1)
  • Alternative technique
    murine
  • Alternative to gene target
    suppressor of cytokine signaling 1, CIS1 and CISH1 and JAB and SOCS-1 and SSI-1 and SSI1 and TIP3, SOCS1 and IDBG-14621 and ENSG00000185338 and 8651, protein kinase binding, nuclei, Socs1 and IDBG-132667 and ENSMUSG00000038037 and 12703, SOCS1 and IDBG-648701 and ENSBTAG00000004386 and 518795
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