Fibrinogen beta chain Antibody

• Catalog number
  bs-10124R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Fibrinogen beta chain Antibody
• Also known as
  Fibrinogen beta chain Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Fibrinogen beta chain
• Specificity
  This is a highly specific antibody against Fibrinogen beta chain.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  420-470/491
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen beta chain
• Gene ID number
  2244
• Swiss Prot
  P02675
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  HEL-S-78p; Fibrinogen beta chain; FGB
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Fibrinogen   beta   chain  
• Gene symbol
  FGB
• Short name
  Anti-Fibrinogen beta chain
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Fibrinogen beta chain Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3662
• Gene
  FGB
• Long gene name
  fibrinogen beta chain
• Synonyms gene name
  • fibrinogen, B beta polypeptide
• Locus
  4q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  2244
• RefSeq identity
  • NM_005141
• Classification
  • Fibrinogen C domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150331
• Locus Specific Databases
  • LRG_558

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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