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STAT1 Ser727 Antibody ALEXA FLUOR

STAT1 Ser727 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-3427R-A350 | STAT1 (Ser727) Antibody, ALEXA FLUOR 350 size: 100ul | 408.10 USD

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bs-3427R-A488 | STAT1 (Ser727) Antibody, ALEXA FLUOR 488 size: 100ul | 408.10 USD

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bs-3427R-A555 | STAT1 (Ser727) Antibody, ALEXA FLUOR 555 size: 100ul | 408.10 USD

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bs-3427R-A594 | STAT1 (Ser727) Antibody, ALEXA FLUOR 594 size: 100ul | 408.10 USD

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bs-3427R-A647 | STAT1 (Ser727) Antibody, ALEXA FLUOR 647 size: 100ul | 408.10 USD

Catalog number bs-3427R-A647
Price 408.10 USD
Size 100ul
Long name STAT1 (Ser727) Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known as Anti-STAT1 Ser727 PAb ALEXA FLUOR 647
Conjugated with ALEXA FLUOR® 647
Excitation emission 650nm/665nm
Properties For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-STAT1 Ser727 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR 647
French translation anticorps
Label ALEXA FLUOR 647
Alternative name STAT1 (Ser727) Polyclonal Antibody, ALEXA FLUOR 647
1. Gene info
Identity 11362
Gene STAT1
Long gene name signal transducer and activator of transcription 1
Synonyms gene name
  • signal transducer and activator of transcription 1, 91kD
  • signal transducer and activator of transcription 1, 91kDa
Synonyms
  • STAT91
  • ISGF-3
Synonyms name
  • transcription factor ISGF-3 components p91/p84
Locus 2q32.2
Discovery year 1995-11-08
Entrez gene record 6772
Pubmed identfication
  • 7885841
RefSeq identity
  • NM_007315
Classification
  • SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000132699
Locus Specific Databases
  • STAT1base: Mutation registry for STAT1 deficiency
  • LRG_111
Product images
    #.png#bs#.jpgSTAT1 (Ser727) Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
Product files
Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen STAT1 Ser727
Specificity This is a highly specific antibody against STAT1 Ser727.
Modification Phosphorylation
Modification Site Ser727
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Immunogen range 700-750/750
Subcellular location Cytoplasm, Nucleus
Source KLH conjugated synthetic phosphopeptide derived from human STAT1 around the phosphorylation site of Ser727
Gene ID Number 6772
Swiss Prot P42224
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human, Mouse, Rat
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1
Gene targetSTAT1 Ser727
Short name Anti-STAT1 Ser727
Technique Antibody
Isotype Immunoglobulin G (IgG)
Alternative technique antibodies
Alternative to gene target signal transducer and activator of transcription 1, 91kDa, CANDF7 and IMD31A and IMD31B and IMD31C and ISGF-3 and STAT91, STAT1 and IDBG-77617 and ENSG00000115415 and 6772, sequence-specific DNA binding, nuclei, Stat1 and IDBG-153162 and ENSMUSG00000026104 and 20846, STAT1 and IDBG-642654 and ENSBTAG00000007867 and 510814,515988
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Anti-STAT1 Ser727 | Technique alternative | 01011192057
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