Cell-permeable. A selective, non-competitive Calpain inhibitor (Ki = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.
Is it cell-permeable?
≥98% by NMR
Is this a salt?
Protect from air and light
Maximum time for storage
DMSO (10 mg/ml) or EtOH (1 mg/ml)
For cells, cell lines and tissues in culture till half confluency.
PD 150,606 for activation
PD 150,606 to measure cellular activation