anti-LEFTY2 Antibody

• Catalog number
  29-698
• Price
  Please ask
• Size
  50 ug

• Gene info
  LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
• Gene names
  LEFTY2, EBAF, LEFTA, LEFTYA, MGC46222, TGFB4
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LEFTY2.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  LEFTY2 antibody can be used for detection of LEFTY2 by ELISA at 1:312500. LEFTY2 antibody can be used for detection of LEFTY2 by western blot at 1.0 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store LEFTY2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  27436881
• Ncbi nr
  NP_003231
• KDa
  40 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  7044
• GENE symbol
  LEFTY2
• Antigene name
  left-right determination factor 2
• Source
  Homo sapiens
• Protein nr
  O00292
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LEFTY2  
• Gene symbol
  LEFTY2
• Short name
  anti-LEFTY2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toleft-right determination factor 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  left-right determination factor 2, EBAF and LEFTA and LEFTYA and TGFB4, LEFTY2 and IDBG-106991 and ENSG00000143768 and 7044, growth factor activity, Extracellular

Gene info

• Identity
  HGNC:3122
• Gene
  LEFTY2
• Long gene name
  left-right determination factor 2
• Synonyms gene
  • TGFB4
  • EBAF
• Synonyms gene name
  • endometrial bleeding associated factor (left-right determination, factor A; transforming growth factor beta superfamily)
• Synonyms
  • LEFTA
  • LEFTYA
• Synonyms name
  • transforming growth factor, beta-4 (endometrial bleeding-associated factor; LEFTY A)
• GenBank acession
  • U81523
• Locus
  1q42.12
• Discovery year
  1998-01-20
• Entrez gene record
  7044
• Pubmed identfication
  • 9153275
• RefSeq identity
  • NM_003240
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000037441

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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