Leukemia BCR-ABL Fusion Gene Typing Real Time RT-PCR Kit

• Catalog number
  TR-0126-01
• Price
  Please ask
• Size
  25tests/kit

• Product type
  Tumor
• Instrument 1
  Ⅰ, Ⅱ
• Instrument 2
  (Ⅰ) LightCycler 1.0 (Internal control can't be used for this system)(Ⅱ) LightCycler 2.0
• Nucleic Acid
  RNA
• Note
  CE Marked
• Description
  Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
• Group
  PCR, polymerase chain reaction, RT-PCR mixes
• About
  TAQ or Pfu or Pfx or other enzymes are used for polycmerase chain reaction and have different specificity. The mores specific the lower the yield.
• Properties
  Thermocyclers can be callibrated for identical ramping curves to obtain a more accurate PCR.

• Gene target
  Leukemia   BCR-ABL   Gene   Typing   Real   Time   Kit  
• Gene symbol
  ABL1, BCRP1, MTTP, BCRP2, BCRP4, BCR
• Short name
  Leukemia BCR-ABL Typing Real Time RT-PCR Kit
• Technique
  RT-PCR, PCR, The polymerase chain reaction (PCR) amplifies the DNA in your sample. For real time PCR the cycle threshold Ct values willneed to be set before the experiment. Than the RT-PCR starts from RNA and real time PCR quantitates the cDNA so the RNA in the sample on given time of the experiment.
• Alternative name
  Leukemia BCR-ABL Fusion Gene Typing Real Time Reverse transcription PCR test kit reagent
• Alternative technique
  rtpcrkits, kits, dna-amplification
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
• Virus
  leukemia

Gene info

• Identity
  HGNC:76
• Gene
  ABL1
• Long gene name
  ABL proto-oncogene 1, non-receptor tyrosine kinase
• Synonyms gene
  • ABL
• Synonyms gene name
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • c-abl oncogene 1, receptor tyrosine kinase
  • c-abl oncogene 1, non-receptor tyrosine kinase
• Synonyms
  • JTK7
  • c-ABL
  • p150
• GenBank acession
  • M14752
• Locus
  9q34.12
• Discovery year
  1986-01-01
• Entrez gene record
  25
• Pubmed identfication
  • 1857987
  • 12626632
• RefSeq identity
  • NM_007313
• Classification
  • Abl family tyrosine kinases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000020813
• Locus Specific Databases
  • LRG_769

Gene info

• Identity
  HGNC:39073
• Gene
  BCRP1
• Long gene name
  BCR pseudogene 1
• Synonyms gene name
  • breakpoint cluster region pseudogene 1
• Synonyms
  • BCR-1
• Locus
  22q11.23
• Discovery year
  2010-09-30
• Entrez gene record
  644079
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_009423
• VEGA ID
  OTTHUMG00000150768

Gene info

• Identity
  HGNC:7467
• Gene
  MTTP
• Long gene name
  microsomal triglyceride transfer protein
• Synonyms gene
  • MTP
• Synonyms gene name
  • microsomal triglyceride transfer protein (large polypeptide, 88kD)
  • microsomal triglyceride transfer protein (large polypeptide, 88kDa)
• Synonyms
  • ABL
• Locus
  4q23
• Discovery year
  1994-12-07
• Entrez gene record
  4547
• Pubmed identfication
  • 8111381
• RefSeq identity
  • NM_000253
• VEGA ID
  OTTHUMG00000131023

Gene info

• Identity
  HGNC:1015
• Gene
  BCRP2
• Long gene name
  BCR pseudogene 2
• Synonyms gene
  • BCR2
  • BCRL2
• Synonyms gene name
  • breakpoint cluster region-like 2
  • breakpoint cluster region pseudogene 2
• Synonyms
  • BCR-2
• Locus
  22q11.21
• Discovery year
  2001-06-22
• Entrez gene record
  400892
• Pubmed identfication
  • 3267213
• RefSeq identity
  • NG_007131
• VEGA ID
  OTTHUMG00000150627

Gene info

• Identity
  HGNC:1017
• Gene
  BCRP4
• Long gene name
  BCR pseudogene 4
• Synonyms gene
  • BCR4
  • BCRL4
• Synonyms gene name
  • breakpoint cluster region-like 4
  • breakpoint cluster region pseudogene 4
• Synonyms
  • BCR-4
• GenBank acession
  • D87002
• Locus
  22q11.22
• Discovery year
  2001-06-22
• Entrez gene record
  616
• Pubmed identfication
  • 9074928
• RefSeq identity
  • NG_000002
• VEGA ID
  OTTHUMG00000151175

Gene info

• Identity
  HGNC:1014
• Gene
  BCR
• Long gene name
  BCR activator of RhoGEF and GTPase
• Synonyms gene
  • D22S11
  • BCR1
• Synonyms gene name
  • breakpoint cluster region
  • BCR, RhoGEF and GTPase activating protein
• Synonyms
  • D22S662
  • CML
  • PHL
  • ALL
• Locus
  22q11.23
• Discovery year
  1986-01-01
• Entrez gene record
  613
• Pubmed identfication
  • 1657398
  • 18070886
• RefSeq identity
  • NM_004327
• Classification
  • C2 domain containing
  • My-T-BRC complex
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000150655
• Locus Specific Databases
  • LRG_1112

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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