HDC2/PHC2 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11291R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  HDC2/PHC2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-HDC2/PHC2 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HDC2/PHC2
• Specificity
  This is a highly specific antibody against HDC2/PHC2.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HDC2/PHC2
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Early development regulatory protein 2;hPH2;early development regulator 2 (homolog of polyhomeotic 2);Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC2 (polyhomeotic-like protein 2), also known as early development regulatory protein 2, is an 858 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Phosphorylated upon DNA damage, PHC2 contains one SAM (sterile alpha motif) domain and one FCS-type zinc finger.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Early development regulatory protein 2; hPH2; early development regulator 2 homolog of polyhomeotic 2; early development regulator 2 like; EDR2; MGC163502; mph2; PH2; PHC2; PHC2_HUMAN; polyhomeotic 2; polyhomeotic like 2; Polyhomeotic-like protein 2.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-HDC2/PHC2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  HDC2/PHC2  
• Gene symbol
  PHC2-AS1, PHC2
• Short name
  Anti-HDC2/PHC2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  HDC2/PHC2 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40205
• Gene
  PHC2-AS1
• Long gene name
  PHC2 antisense RNA 1
• Locus
  1p35.1
• Discovery year
  2019-09-19
• Entrez gene record
  101929464
• RefSeq identity
  • NR_125978
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3183
• Gene
  PHC2
• Long gene name
  polyhomeotic homolog 2
• Synonyms gene
  • EDR2
• Synonyms gene name
  • early development regulator 2 (homolog of polyhomeotic 2)
  • polyhomeotic-like 2 (Drosophila)
  • polyhomeotic homolog 2 (Drosophila)
• Synonyms
  • HPH2
• GenBank acession
  • AJ419231
• Locus
  1p35.1
• Discovery year
  1997-09-12
• Entrez gene record
  1912
• Pubmed identfication
  • 9121482
  • 12384788
• RefSeq identity
  • NM_198040
• Classification
  • Sterile alpha motif domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000004133

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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