anti-PTHR1 Antibody, Monoclonal

• Catalog number
  49-809
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.
• Gene names
  PTH1R, Parathyroid hormone 1 receptor, Parathyroid hormone receptor 1, PFE, Pth-related peptide receptor, PTHR, PTH/PTHr receptor, Pth/pthrp receptor, Parathyroid hormone receptor, PTH/PTHrP type I receptor, PTH1 receptor, PTHR1, PTHrP-R, PTHrP-receptor
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Mouse
• Type
  Monoclonal
• Immunoglobulin
  IgG1,k
• Spicific to
  Recognizes human PTH/PTHrP receptor, Mr 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.
• Antigen
  PTHR1 monoclonal antibody was made against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human).
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  PTHR1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 15 ug/mL.
• Suspention pH azide
  PBS, pH 7.6, 0.07% sodium azide, 30% glycerol
• Keep at
  PTHR1 antibody should be stored long term (months) at -20 grades C and short term (weeks) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Gibbon, Bovine, Dog, Gorilla, Horse, Human, Monkey, Orangutan, Pig
• Omim nr
  417555
• Ncbi nr
  Q03431
• Vial with antibody
  in solution
• NCBI GENE nr
  5745
• GENE symbol
  PTH1R
• Antigene name
  parathyroid hormone 1 receptor
• Source
  Homo sapiens
• Protein nr
  Q03431
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  PTHR1   Monoclonal  
• Gene symbol
  PTH1R
• Short name
  anti-PTHR1 Antibody, Monoclonal
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Alternative name
  Antibody toPTHR1 (antibody to-), monoclonal
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9608
• Gene
  PTH1R
• Long gene name
  parathyroid hormone 1 receptor
• Synonyms gene
  • PTHR
  • PTHR1
• Synonyms gene name
  • parathyroid hormone receptor 1
• Locus
  3p21.31
• Discovery year
  1993-03-23
• Entrez gene record
  5745
• Pubmed identfication
  • 8020952
• RefSeq identity
  • NM_000316
• Classification
  • Parathyroid hormone receptors
• VEGA ID
  OTTHUMG00000133515

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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