Biotinylated Glucose AGE-BSA-II

  • Catalog number
    7930-1000
  • Price
    Please ask
  • Size
    1 mg
  • Description
    AGEs can bind a variety of receptors. Biotinylation of Glucose-AGE-BSA allows for its purification by Streptavidin-Sepharose beads. Advanced glycation end products (AGEs) accumulate with age and at an accelerated rate in diabetes. AGEs bind cell-surface receptors including the receptor for AGE (RAGE). AGEs therefore have been implicated in the pathogenesis of diabetes, induction of proinflammatory cytokines, and stimulation of smooth muscle proliferation, and fibronectin production. The Biotinylated Glucose AGE-BSA-II was produced by biotinylation of Glucose AGE-BSA-II (Cat. # 2223-10) with Sulfo-NHS-LC-Biotin (Cat # 2326). Prior to biotinylation, The Glucose AGE BSA II was produced by reacting BSA with glucose under sterile conditions followed by extensive dialysis and purification steps. Fluorescence of AGEs was confirmed by fluorescence spectrophotometry with Ex/Em = 370/440 nm. Glycated BSA shows >50X increase in fluorescence in compared to control BSA.
  • Product Highlights
    FORM: Liquid. FORMULATION: 5 mg/ml of 0.22 µm filter sterilized solution in 1X PBS LABELING EFFICIENCY: BioVision’s Biotinylated Glucose AGE-BSA-II was estimated to contain ~1-2 biotin/BSA (As tested using Biotin Quantitation Kit (K811-100)). APPLICATIONS: Biotinylation of Glucose AGE-BSA-II allows for its pull-down by Streptavidin-Sepharose beads (Cat. # 6565).
  • Storage Temp
    -70°C
  • Shipping
    gel pack
  • Shelf Life
    12 months
  • Notes
    For research use only. Not to be used for human or animal treatment or consumption.
  • Gene target
  • Gene symbol
    CRABP2, SPINK2, MGST2, IBSP, APOL2, MGAT2, P4HA2, TMED10P1, XYLT2, PSMB3
  • Short name
    Biotinylated Glucose AGE-BSA-II
  • Alternative name
    Biotinylated Glucose AGE-cow serum albumin-II
Gene info
  • Identity
  • Gene
  • Long gene name
    cellular retinoic acid binding protein 2
  • Synonyms gene name
    • cellular retinoic acid-binding protein 2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1992-11-25
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Fatty acid binding protein family
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    transmembrane p24 trafficking protein 10 pseudogene 1
  • Synonyms gene
  • Synonyms gene name
    • transmembrane emp24-like trafficking protein 10 (yeast) pseudogene
    • transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2005-08-26
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    proteasome 20S subunit beta 3
  • Synonyms gene name
    • proteasome (prosome, macropain) subunit, beta type, 3
    • proteasome subunit beta 3
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1995-05-03
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Proteasome
  • VEGA ID
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