M-CSF

Catalog number

E21-417
Price

Please ask
Size

10ug

Shipping_Temperature

Ambient
Product_State

Lyophilized
Formulation_Description

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Storage

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin

Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Background

Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Alternative Names

Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1
Expression system

Human cells

Gene target

M-CSF
Gene symbol

CSF1, CPT1B, CSF2, IRAK3, PGAM2, CYP20A1, USP16, CYB5B, H3C14, CSF3
Short name

M-CSF
Species

Human
Alternative name

M-CSF

Gene info

Identity

HGNC:2432
Gene

CSF1
Long gene name

colony stimulating factor 1
Synonyms gene name
- colony stimulating factor 1 (macrophage)
Synonyms
- M-CSF
- MCSF
- MGC31930
Synonyms name
- macrophage colony stimulating factor 1
GenBank acession
- BC021117
Locus

1p13.3
Discovery year

1986-01-01
Entrez gene record

1435
Pubmed identfication
- 1540160
RefSeq identity
- NM_000757
VEGA ID

OTTHUMG00000011646

Gene info

Identity

HGNC:2329
Gene

CPT1B
Long gene name

carnitine palmitoyltransferase 1B
Synonyms gene name
- carnitine palmitoyltransferase 1B (muscle)
Synonyms
- M-CPT1
- CPT1-M
Synonyms name
- carnitine O-palmitoyltransferase 1B
GenBank acession
- U62733
Locus

22q13.33
Discovery year

1996-08-14
Entrez gene record

1375
Pubmed identfication
- 9070950
RefSeq identity
- NM_152246
VEGA ID

OTTHUMG00000137390

Gene info

Identity

HGNC:2434
Gene

CSF2
Long gene name

colony stimulating factor 2
Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
Synonyms
- GM-CSF
- GMCSF
Synonyms name
GenBank acession
- M11734
Locus

5q31.1
Discovery year

2001-06-22
Entrez gene record

1437
Pubmed identfication
- 3898082
- 2999978
RefSeq identity
- NM_000758
VEGA ID

OTTHUMG00000059637

Gene info

Identity

HGNC:17020
Gene

IRAK3
Long gene name

interleukin 1 receptor associated kinase 3
Synonyms gene name
- interleukin-1 receptor-associated kinase 3
Synonyms
- IRAK-M
GenBank acession
- AF113136
Locus

12q14.3
Discovery year

2002-07-17
Entrez gene record

11213
Pubmed identfication
- 10383454
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000169002

Gene info

Identity

HGNC:8889
Gene

PGAM2
Long gene name

phosphoglycerate mutase 2
Synonyms gene name
- phosphoglycerate mutase 2 (muscle)
Synonyms
- PGAM-M
Locus

7p13
Discovery year

1989-06-30
Entrez gene record

5224
Classification
- Phosphoglycerate mutases
- Bisphosphoglycerate phosphatases
VEGA ID

OTTHUMG00000155355

Gene info

Identity

HGNC:20576
Gene

CYP20A1
Long gene name

cytochrome P450 family 20 subfamily A member 1
Synonyms gene name
- cytochrome P450, family 20, subfamily A, polypeptide 1
Synonyms
- CYP-M
GenBank acession
- AK021770
Locus

2q33.2
Discovery year

2003-03-20
Entrez gene record

57404
RefSeq identity
- NM_020674
Classification
- Cytochrome P450 family 20
VEGA ID

OTTHUMG00000132854

Gene info

Identity

HGNC:12614
Gene

USP16
Long gene name

ubiquitin specific peptidase 16
Synonyms gene name
- ubiquitin specific protease 16
Synonyms
- Ubp-M
GenBank acession
- AF126736
Locus

21q21
Discovery year

1999-07-09
Pubmed identfication
- 12838346
Classification
- Ubiquitin specific peptidases
VEGA ID

OTTHUMG00000078802

Gene info

Identity

HGNC:24374
Gene

CYB5B
Long gene name

cytochrome b5 type B
Synonyms gene name
- cytochrome b5 type B (outer mitochondrial membrane)
Synonyms
- CYB5-M
Locus

16q22.1
Discovery year

2006-01-30
Entrez gene record

80777
Pubmed identfication
- 11867265
- 14733950
RefSeq identity
- NM_030579
VEGA ID

OTTHUMG00000133020

Gene info

Identity

HGNC:20503
Gene

H3C14
Long gene name

H3 clustered histone 14
Synonyms gene
- H3F2
- H3FM
- HIST2H3C
Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
Synonyms
- MGC9629
- H3/m
- H3
- H3.2
- H3/M
GenBank acession
- AF531307
Locus

1q21.2
Discovery year

2003-02-19
Entrez gene record

126961
Pubmed identfication
- 12408966
- 3013246
RefSeq identity
- NM_021059
Classification
- H3 histones
VEGA ID

OTTHUMG00000012190

Gene info

Identity

HGNC:2438
Gene

CSF3
Long gene name

colony stimulating factor 3
Synonyms gene
- GCSF
- G-CSF
- C17orf33
Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
Synonyms
- MGC45931
Synonyms name
Locus

17q21.1
Discovery year

2001-06-22
Entrez gene record

1440
Pubmed identfication
- 3499671
- 3501046
RefSeq identity
- NM_172220
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000133247

M-CSF

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Gene info

Similar products

Ask M-CSF selection audit