PYCARD, CT (ASC, Apoptosis-associated Speck-like Protein Containing a CARD, hASC, Caspase Recruitment Domain-containing Protein 5, PYD and CARD Domain-containing Protein, Target of Methylation-induced Silencing 1, CARD5, TMS1)

• Catalog number
  MBS645543
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [PYCARD]
• Products_name_syn
  [Anti -PYCARD, CT (ASC, Apoptosis-associated Speck-like Protein Containing a CARD, hASC, Caspase Recruitment Domain-containing Protein 5, PYD and CARD Domain-containing Protein, Target of Methylation-induced Silencing 1, CARD5, TMS1)]
• Other_names
  [PYCARD; Apoptosis-associated speck-like protein containing a CARD; apoptosis-associated speck-like protein containing a CARD; target of methylation-induced silencing 1; caspase recruitment domain-containing protein 5; PYD and CARD domain containing; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1]
• Other_gene_names
  [PYCARD; PYCARD; ASC; TMS; TMS1; CARD5; TMS-1; ASC; CARD5; TMS1; hASC]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human PYCARD.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  This 1 is suited for programmed cell-death studies. Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.
• Gene
  Non-methylated DNA at CpG islands organizes histone methylation through ZF-CxxC proteins in epigenetic biological systems. DNA and histone Methylation is catalyzed by enzymes; such methylation can be involved in hodyonr modification, regulation of gene expression, regulation of protein function, and RNA processing. Methylation of heavy metals can also occur outside biological systems. Chemical methylation of tissue samples is also one method for reducing certain histological staining artifacts. The counterpart of methylation is demethylation.

• Gene target
  PYCARD   ASC   associated   Speck-like   Protein   CARD   hASC   Caspase   Recruitment   Domain   Protein   PYD   CARD   Domain   Protein   Methylation   Silencing   CARD5   TMS1  
• Gene symbol
  PYCARD, SLC7A10, PYCARD-AS1, TRIP4
• Short name
  PYCARD, CT (ASC, Apoptosis-associated Speck-like Protein a CARD, hASC, Caspase Recruitment Domain- Protein 5, PYD CARD Domain- Protein, of - Silencing 1, CARD5, TMS1)
• Technique
  apoptosis, apoptosis pathway
• Host
  Goat
• Alternative name
  PYD and CARD domain containing, CT (ASC, programmed cellular destruction-associated Speck-like Protein Containing a CARD, hASC, caspase Recruitment Domain-containing Protein 5, PYD and CARD Domain-containing Protein, Target on Methylation-induced Silencing 1, CARD5, TMS1)
• Alternative technique
  celldeath
• Alternative to gene target
  PYD and CARD domain containing, PYCARD and IDBG-28012 and ENSG00000103490 and 29108, protein homodimerization activity, nuclei, Pycard and IDBG-210514 and ENSMUSG00000030793 and 66824, PYCARD and IDBG-639579 and ENSBTAG00000020535 and 282846

Gene info

• Identity
  HGNC:16608
• Gene
  PYCARD
• Long gene name
  PYD and CARD domain containing
• Synonyms
  • TMS-1
  • CARD5
  • ASC
• Synonyms name
  • apoptosis-associated speck-like
  • apoptosis-associated speck-like protein containing a CARD
• GenBank acession
  • AB023416
• Locus
  16p11.2
• Discovery year
  2004-06-25
• Entrez gene record
  29108
• Pubmed identfication
  • 11250163
  • 10567338
  • 11103776
• RefSeq identity
  • NM_013258
• Classification
  • Pyrin domain containing
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000176753

Gene info

• Identity
  HGNC:11058
• Gene
  SLC7A10
• Long gene name
  solute carrier family 7 member 10
• Synonyms gene name
  • solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
• Synonyms
  • asc-1
• GenBank acession
  • AB037670
• Locus
  19q13.11
• Discovery year
  2000-06-02
• Entrez gene record
  56301
• Pubmed identfication
  • 10734121
  • 10863037
• RefSeq identity
  • NM_019849
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000180344

Gene info

• Identity
  HGNC:45036
• Gene
  PYCARD-AS1
• Long gene name
  PYCARD antisense RNA 1
• Synonyms gene
  • C16orf98
  • PYCARDOS
• Synonyms gene name
  • chromosome 16 open reading frame 98
  • PYCARD opposite strand
• Locus
  16p11.2
• Discovery year
  2013-01-22
• Entrez gene record
  100652740
• RefSeq identity
  • NR_102400
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000132405

Gene info

• Identity
  HGNC:12310
• Gene
  TRIP4
• Long gene name
  thyroid hormone receptor interactor 4
• Synonyms
  • HsT17391
  • ZC2HC5
  • ASC-1
• Synonyms name
  • zinc finger, C2HC5-type
  • Activating Signal Cointegrator-1
• GenBank acession
  • L40371
• Locus
  15q22.31
• Discovery year
  1999-03-19
• Entrez gene record
  9325
• Pubmed identfication
  • 7776974
  • 12077347
• RefSeq identity
  • NM_016213
• Classification
  • Activating signal cointegrator 1 complex
  • Zinc fingers
• VEGA ID
  OTTHUMG00000133033

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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