RUNX2, phosphorylated (Ser465) (Runt-related Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A,

  • Catalog number
    MBS630580
  • Price
    Please ask
  • Size
    0.2 mL
  • Products_type
    Antibody
  • Products_short_name
    [RUNX2]
  • Products_name_syn
    [Anti -RUNX2, phosphorylated (Ser465) (Runt-related Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A,]
  • Other_names
    [runt-related transcription factor 2; Runt-related transcription factor 2; runt-related transcription factor 2; CBF-alpha-1; PEA2-alpha A; PEBP2-alpha A; oncogene AML-3; OTTHUMP00000016533; OTTHUMP00000016534; OTTHUMP00000016535; acute myeloid leukemia 3 protein; SL3-3 enhancer factor 1 alpha A subunit; osteoblast-specific transcription factor 2; SL3/AKV core-binding factor alpha A subunit; core-binding factor, runt domain, alpha subunit 1; polyomavirus enhancer-binding protein 2 alpha A subunit; runt-related transcription factor 2]
  • Other_gene_names
    [RUNX2; RUNX2; CCD; AML3; CCD1; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1; MGC120022; MGC120023]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    RRecognizes human RUNX2 when phosphorylated at Ser465.
  • Purity
    Affinity Purified Purified by Protein A affinity chromatography.
  • Form
    Supplied as a liquid in PBS, 0.09% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)
  • Description
    The RUNX2, phosphorylated (Ser465) (Runt- Transcription Factor 2, Core-binding Factor Subunit alpha-1, CBF-alpha-1, Acute Myeloid Leukemia 3 Protein, Oncogene AML-3, Polyomavirus Enhancer-binding Protein 2 alpha A Subunit, PEBP2-alpha A, PEA2-alpha A, is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:53512
  • Gene
    RUNX2-AS1
  • Long gene name
    RUNX2 antisense RNA 1
  • Locus
    6p21.1
  • Discovery year
    2017-05-12
  • Entrez gene record
    105375077
  • Classification
    • Antisense RNAs
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:37518
  • Gene
    PIRC14
  • Long gene name
    piwi-interacting RNA cluster 14
  • Locus
    3
  • Discovery year
    2009-11-05
  • Entrez gene record
    100313784
  • Pubmed identfication
  • Classification
    • Piwi-interacting RNA clusters
MeSH Data
  • Name
    Leukemia, Experimental
  • Concept
    Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
  • Tree numbers
    • C04.557.337.372
    • C04.619.531
    • E05.598.500.496.500
  • Qualifiers
    diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery
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RUNX2 phosphorylated Ser465) (Runt Transcription Factor 2 Co
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