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PF 573228 for cell activation

PF 573228 for cell activation is available 2 times from Biovision labs

2819-50 | PF-573228 for cell activation size: 50 mg | 667.14 USD

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2819-10 | PF-573228 for cell activation size: 10 mg | 198.56 USD

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Other name 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone
Supplied with N/A
Description PF-573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC₅₀ = 4 nM). PF-573,228 inhibits FAK phosphorylation on Tyr(397) with an IC₅₀ of 30-100 nM.  Displays 50 - 250-fold selectivity for FAK over other protein kinases. Blocks serum and fibronectin-directed migration and decreases focal adhesion turnover in vitro.
Category Biochemicals
Molecular formula C₂₂H₂₀F₃N₅O₃S
Is it cell-permeable? yes
Molecular weight 491.49
Storage condition -20°C
Shipping condition Gel Pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 869288-64-2
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Off-white solid
Reconstitute instructions DMSO (>40 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name PF-573228 for activation
Technique activation
Alternative name PF-573228 to measure cellular activation
Tissue cell
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