-
Alternative name1
Anti-RABBIT ANTI HUMAN FRACTALKINE:Biotin
-
Alternative name2
RABBIT ANTI HUMAN FRACTALKINE:Biotin
-
Alternative name3
Lapin ANTI Homo sapiens FRACTALKINE:Biotin
-
Alternative name4
FRACTALKINE
-
Alternative name5
N/A
-
Other names
fractalkine; Fractalkine; fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); chemokine (C-X3-C motif) ligand 1; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
-
Gene name
N/A
-
Gene name synonims
N/A
-
Other gene names
CX3CL1; CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin; FKN; NTT; SCYD1
-
Category
Antibodies
-
Clonality
Polyclonal
-
Immunoglobulin isotype
Polyclonal IgG
-
Clone
Polyclonal antibody
-
Host organism
Rabbit
-
Species reactivity
Human
-
Specificity and cross reactivity
FRACTALKINE This item is specific for human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle. Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and studies have suggested that fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes CX3CL1 may also play a role in dendritic cell-mediated host defense against invading pathogens such as Legionella pneumophila
-
Purification method
N/A
-
Form Appearance
Biotin (Purified IgG conjugated to Biotin - lyophilised)
-
Concentration
IgG concentration 50ug/ml
-
Storage and shipping
Prior to reconstitution store at +Store productone at +4 degrees Celsius.. Following reconstitution For optimal long term storage, productone should be kept at -20 degrees Celsius. productone should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
-
Tested for
ELISA (EIA), Western Blot (WB)
-
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
-
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
-
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
-
Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Conjugation
Biotinylated
