Recombinant Single Ig IL1 Related Receptor (SIGIRR)

Estimated Turnaround Time

6-11 business days
Gene Name

NA
Alternative Names

TIR8; Single Ig IL-1R-related molecule; Toll/interleukin-1 receptor 8; Single immunoglobulin domain-containing IL1R-related protein
Source

E.coli
Purity

≥ 92%
Application

Positive Control; Immunogen; SDS-PAGE; WB.
Shipping Conditions

Ice packs
Storage conditions

Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Shelf life

1 year
Restriction

For research use only. Not for diagnostic procedures.
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source

Recombinants or rec. proteins
Group

recombinants

Gene target

Single IL1 Related Receptor SIGIRR
Gene symbol

IL1A, SIGIRR, IL1B, IL36A, IL1F10, IL36B
Short name

Recombinant Single Ig IL1 Receptor (SIGIRR)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Homo sapiens (Human)
Alternative name

Rec. Single Ig IL1 Related Receptor (single immunoglobulin and toll-interleukin 1 receptor (TIR) domain)
Alternative technique

rec
Alternative to gene target

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, SIGIRR and IDBG-16551 and ENSG00000185187 and 59307, protein binding, Plasma membranes, Sigirr and IDBG-211977 and ENSMUSG00000025494 and 24058, SIGIRR and IDBG-645604 and ENSBTAG00000011149 and 531801

Identity

HGNC:30575
Gene

SIGIRR
Long gene name

single Ig and TIR domain containing
Synonyms gene name
- single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Synonyms
- TIR8
- IL-1R8
Synonyms name
- single immunoglobulin domain IL1R1 related
Locus

11p15.5
Discovery year

2005-10-10
Entrez gene record

59307
Pubmed identfication
- 10346978
RefSeq identity
- NM_021805
Classification
- TIR domain containing
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000165412

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data