anti-INHA Antibody [4A2A9 / 4A2F7 / 4A2F2]
-
Catalog number
32-181
-
Price
Please ask
-
Size
0.1 mg
-
-
Gene info
INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
-
Gene names
Inhibin alpha chain
-
Antibodie s label
unlabelled serum
-
Purity
Antibody is purified by protein A affinity chromatography.
-
Ab raised in
Mouse
-
Type
Monoclonal
-
Monoclonal
4A2A9 / 4A2F7 / 4A2F2
-
Immunoglobulin
IgG1
-
Antigen
Ni-NTA purified truncated recombinant INHA expressed in E. Coli strain BL21 (DE3).
-
Immuno application
ELISA, Western Blot, immuno-histo-chemistry
-
Antibody advice
Western Blot:1:500 - 1:1,000 IHC(P):1:1,000 - 1:2,000ELISA:Propose dilution 1:10,000Determining optimal working dilutions by titration test.
-
Suspention pH azide
Purified antibody in PBS containing 0.03% sodium azide
-
Keep at
INHA(Inhibin alpha) monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works with
Human
-
Omim nr
124274
-
Ncbi nr
P05111
-
NCBI GENE nr
3623
-
GENE symbol
INHA
-
Antigene name
inhibin, alpha
-
Source
Homo sapiens
-
Protein nr
P05111
-
-
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translation
anticorps
-
Gene target
-
Gene symbol
INHA
-
Short name
anti-INHA Antibody [4A2A9 / 4A2F7 / 4A2F2]
-
Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative name
Antibody toINHA (antibody to-) [4A2A9 / 4A2F7 / 4A2F2]
-
Alternative technique
antibodies
-
Alternative to gene target
inhibin, alpha, INHA and IDBG-81968 and ENSG00000123999 and 3623, protein heterodimerization activity, Extracellular, Inha and IDBG-171659 and ENSMUSG00000032968 and 16322, INHA and IDBG-644083 and ENSBTAG00000009972 and 281254
-
Gene info
-
Identity
-
Gene
-
Long gene name
inhibin subunit alpha
-
Synonyms gene name
-
Locus
-
Discovery year
2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products