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Products_type
Antibody
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Products_short_name
[MDM2]
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Products_name_syn
[Anti-MDM2 Antibody (aa154-167, clone SMP14) IHC-plus; MDM2; ACTFS; Double minute 2 protein; Hdm2; MDM2 variant FB30; HDMX; Oncoprotein Mdm2; p53-binding protein Mdm2; MDM2 variant FB28; Human MDM2]
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Other_names
[E3 ubiquitin-protein ligase Mdm2 isoform a; E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; oncoprotein Mdm2; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2, p53 E3 ubiquitin protein ligase homolog; double minute 2, human homolog of; p53-binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MDM2 proto-oncogene, E3 ubiquitin protein ligase; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2]
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Products_gene_name
[MDM2]
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Other_gene_names
[MDM2; MDM2; HDMX; hdm2; ACTFS; Hdm2]
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Clonality
Monoclonal
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Clone
[SMP14]
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Reactivity
Gibbon, Dog, Human, Monkey, Orangutan, Rat Predicted Reactivity: Bat, Bovine, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
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Specificity
Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2
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Purity
Purified IgG
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Form
PBS, 0.09% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
+4 degree C or -20 degree C, Avoid repeated freezing and thawing. Store undiluted.
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Tested_application
Immunohistochemistry (IHC - Paraffin; IHC - Frozen; IHC - Resin), Western Blot (WB), Immunoprecipitation (IP)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
