BRCA1 (Phospho-Ser1457) Antibody

• Catalog number
  A8306-A
• Price
  Please ask
• Size
  100 µg

• Applications
  WB ELISA
• Source
  Rabbit
• Reactivity
  H
• MW kDa
  207 kDa
• Target Modification
  Phospho
• Modification Sites
  H:S1457
• Immunogen
  The antiserum was produced against synthesized peptide derived from human BRCA1 around the phosphorylation site of Ser1457.
• Immunogen Range
  1423-1472
• Purification
  The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
• Specificity
  BRCA1 (Phospho-Ser1457) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1457.
• Gene ID
  672
• Swiss Prot No
  P38398
• OMIM No
  113705/114480
• Unigene No
  Hs.194143
• NCBI Gene Symbol
  BRCA1
• Synonyms
  BRCA1; Breast cancer type 1 susceptibility protein; familial breast/ovarian cancer gene 1
• Storage Stability
  Stable at -20°C for at least 1 year.
• Physical Form
  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Clonality
  Polyclonal
• Concentration
  1 mg/ml
• Properties
  If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BRCA1   Phospho-Ser1457  
• Gene symbol
  BRCA1, BRCA1P1
• Short name
  BRCA1 (Phospho-Ser1457) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  breast cancer 1, early onset (phosphorilated-Ser1457) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  breast cancer 1, early onset, BRCAI and BRCC1 and BROVCA1 and IRIS and PNCA4 and PPP1R53 and PSCP and RNF53, BRCA1 and IDBG-52172 and ENSG00000012048 and 672, androgen receptor binding, nuclei, Brca1 and IDBG-212218 and ENSMUSG00000017146 and 12189, BRCA1 and IDBG-640630 and ENSBTAG00000022520 and 353120

Gene info

• Identity
  HGNC:1100
• Gene
  BRCA1
• Long gene name
  BRCA1 DNA repair associated
• Synonyms gene name
  • breast cancer 1, early onset
  • breast cancer 1
• Synonyms
  • RNF53
  • BRCC1
  • PPP1R53
  • FANCS
• Synonyms name
  • BRCA1/BRCA2-containing complex, subunit 1
  • protein phosphatase 1, regulatory subunit 53
  • Fanconi anemia, complementation group S
• GenBank acession
  • U14680
• Locus
  17q21.31
• Discovery year
  1991-02-20
• Entrez gene record
  672
• Pubmed identfication
  • 1676470
  • 25472942
• RefSeq identity
  • NM_007294
• Classification
  • Ring finger proteins
  • Protein phosphatase 1 regulatory subunits
  • BRCA1 A complex
  • BRCA1 B complex
  • BRCA1 C complex
  • FA complementation groups
• VEGA ID
  OTTHUMG00000157426
• Locus Specific Databases
  • Breast Cancer
  • Fanconi Anaemia Mutation Database
  • BRCA1 database at LOVD-China
  • Global Variome shared LOVD
  • LOVD - Leiden Open Variation Database
  • LRG_292

Gene info

• Identity
  HGNC:28470
• Gene
  BRCA1P1
• Long gene name
  BRCA1 pseudogene 1
• Synonyms
  • LBRCA1
  • PsiBRCA1
  • pseudo-BRCA1
• Synonyms name
  • like-BRCA1
• Locus
  17q21.31
• Discovery year
  2005-05-26
• Entrez gene record
  394269
• Pubmed identfication
  • 11880951
  • 8954804
  • 10205276
• RefSeq identity
  • NG_003183

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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