ROCK Inhibitor (Rockout)
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Catalog number2342-25
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PricePlease ask
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Size25 mg
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Alternative_name3-(4-Pyridyl)-1H-indole
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DescriptionA cell-permeable, ATP-competitive inhibitor of Rho kinase (ROCK) activity in vitro (IC₅₀ = 25 µM). Inhibits blebbing o trypsinized Swiss3T3 and M2 cells.
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CAS Number7272-84-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₃H₁₀N₂
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Molecular Weight194.23
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (25 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent Rho kinase (ROCK) inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID644354
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SMILESC1=CC=C2C(=C1)C(=CN2)C3=CC=NC=C3
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InChiInChI=1S/C13H10N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-9,15H
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InChi KeyLLJRXVHJOJRCSM-UHFFFAOYSA-N
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MSDS AvailableYes
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Short nameROCK Inhibitor (Rockout)
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Alternative nameROCK suppressor (Rockout)
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