ROCK Inhibitor (Rockout)

• Catalog number
  2342-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  3-(4-Pyridyl)-1H-indole
• Description
  A cell-permeable, ATP-competitive inhibitor of Rho kinase (ROCK) activity in vitro (IC₅₀ = 25 µM). Inhibits blebbing o trypsinized Swiss3T3 and M2 cells.
• CAS Number
  7272-84-6
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₁₀N₂
• Molecular Weight
  194.23
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (25 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent Rho kinase (ROCK) inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  644354
• PubChem CID Link
• SMILES
  C1=CC=C2C(=C1)C(=CN2)C3=CC=NC=C3
• InChi
  InChI=1S/C13H10N2/c1-2-4-13-11(3-1)12(9-15-13)10-5-7-14-8-6-10/h1-9,15H
• InChi Key
  LLJRXVHJOJRCSM-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes
• Additional description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  ROCK   Inhibitor   Rockout  
• Short name
  ROCK Inhibitor (Rockout)
• Alternative name
  ROCK suppressor (Rockout)

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