PKI-402

  • Catalog number
    B1727-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    PKI-402; PKI402; PKI 402; 1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea; 3-{4-[3-ethyl-7-(morpholin-4-yl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]phenyl}-1-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea
  • Description
    PKI-402 is a potent dual inhibitor of PI3K/mTOR with IC50 values of 2 nM/7 nM/16 nM/14 nM and 3 nM for PI3Kα/β/γ/δ and mTOR, respectively.
  • CAS Number
    1173204-81-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₉H₃₄N₁₀O₃
  • Molecular Weight
    570.65
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent dual inhibitor of PI3K/mTOR
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD18251484
  • PubChem CID
    44187953
  • SMILES
    CCN1C2=C(C(=NC(=N2)C3=CC=C(C=C3)NC(=O)NC4=CC=C(C=C4)C(=O)N5CCN(CC5)C)N6CCOCC6)N=N1
  • InChi
    InChI=1S/C29H34N10O3/c1-3-39-27-24(34-35-39)26(37-16-18-42-19-17-37)32-25(33-27)20-4-8-22(9-5-20)30-29(41)31-23-10-6-21(7-11-23)28(40)38-14-12-36(2)13-15-38/h4-11H,3,12-19H2,1-2H3,(H2,30,31,41)
  • InChi Key
    ZAXFYGBKZSQBIV-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    PKI-402  
  • Short name
    PKI-402
  • Alternative name
    PKI-402
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