SARA Antibody, ALEXA FLUOR 488

• Catalog number
  bs-19393R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  SARA Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-SARA PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SARA
• Specificity
  This is a highly specific antibody against SARA .
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  80-130/1425
• Subcellular location
  Cytoplasm, Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SARA
• Gene ID Number
  9372
• Swiss Prot
  O95405
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  NSP; SARA; MADHIP; SMADIP; PPP1R173; Zinc finger FYVE domain-containing protein 9; Mothers against decapentaplegic homolog-interacting protein; Madh-interacting protein; Novel serine protease; Receptor activation anchor; hSARA; Smad anchor for receptor activation; ZFYVE9
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SARA has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  SARA  
• Gene symbol
  SAR1A, ZFYVE9
• Short name
  Anti-SARA
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  SARA Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10534
• Gene
  SAR1A
• Long gene name
  secretion associated Ras related GTPase 1A
• Synonyms gene
  • SARA1
• Synonyms gene name
  • SAR1a gene homolog (S. cerevisiae) 1
  • SAR1a gene homolog 1 (S. cerevisiae)
  • SAR1 homolog A (S. cerevisiae)
  • secretion associated, Ras related GTPase 1A
• Synonyms
  • SAR1
  • Sara
• Locus
  10q22.1
• Discovery year
  2000-06-28
• Entrez gene record
  56681
• Pubmed identfication
  • 10871277
  • 32358066
• Classification
  • COPII coat complex
  • ARF GTPase family
• VEGA ID
  OTTHUMG00000018400

Gene info

• Identity
  HGNC:6775
• Gene
  ZFYVE9
• Long gene name
  zinc finger FYVE-type containing 9
• Synonyms gene
  • MADHIP
• Synonyms gene name
  • MAD, mothers against decapentaplegic homolog (Drosophila) interacting protein, receptor activation anchor
  • zinc finger, FYVE domain containing 9
• Synonyms
  • SMADIP
  • SARA
  • PPP1R173
• Synonyms name
  • protein phosphatase 1, regulatory subunit 173
• GenBank acession
  • AF104304
• Locus
  1p32.3
• Discovery year
  2000-06-08
• Entrez gene record
  9372
• Pubmed identfication
  • 9865696
• RefSeq identity
  • NM_007324
• Classification
  • Zinc fingers FYVE-type
• VEGA ID
  OTTHUMG00000008061

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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