NFkB, p50, GST (delta434-969) (NF-kB, Nuclear Factor kappa B p50 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B cells 1, NFkB1, DKFZp686C01211, DNA Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, NF-kB, Nuclear Factor kappa

  • Catalog number
    MBS658769
  • Price
    Please ask
  • Size
    0.05 mg
  • Products_type
    Peptide
  • Products_short_name
    [NFkB, p50, GST]
  • Products_name_syn
    [NFkB, p50, GST (delta434-969) (NF-kB, Nuclear Factor kappa B p50 Subunit, Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B cells 1, NFkB1, DKFZp686C01211, DNA Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, NF-kB, Nuclear Factor kappa]
  • Purity
    Highly PurifiedPurified by Glutathione agarose chromatography. 90%, determined by SDS-PAGE and Coomassie blue staining.
  • Form
    Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1% beta-mercaptoethanol, 0.03% Brij-35, 0.2mM PMSF, 1mM benzamidine and 50% glycerol.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
  • Gene
    NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
  • Gene target
    NFkB   p50   GST   delta434-969   NF-kB   Factor   kappa   p50   Subunit   Factor   kappa   Light   Polypeptide   Gene   Enhancer   cells   NFkB1   DKFZp686C01211   DNA   Binding   Factor   KBF1   EBP-1   KBF1   MGC54151   NF-kappa-B   NF-kB   Factor   kappa  
  • Gene symbol
    NFKB1, NFE4, NFE2, NEFH, INA, NFASC, NFATC1, NFATC2, NFYC, NFIL3
  • Short name
    NFkB, p50, GST (delta434-969) (NF-kB, Factor kappa B p50 Subunit, Factor of kappa Light Polypeptide Enhancer in B cells 1, NFkB1, DKFZp686C01211, DNA Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, NF-kB, Factor kappa
  • Technique
    light, dna
  • Host
    E Coli
  • Alternative name
    NFkB, p50, GST (delta434-969) (NF-kB, Nuclear Factor kappa B p50 functionnal sequence, Nuclear Factor on kappa Light multipeptide Gene Enhancer in B cells 1, nuclear factor on kappa light polypeptide gene enhancer in B-cells 1, DKFZp686C01211, Desoxyribonucleic acid Binding Factor KBF1, EBP-1, KBF1, MGC54151, NF-kappa-B, NF-kB, Nuclear Factor kappa
  • Alternative to gene target
    nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, EBP-1 and KBF1 and NF-kappa-B and NF-kappaB and NF-kB1 and NFkappaB and NFKB-p105 and NFKB-p50 and p105 and p50, NFKB1 and IDBG-31974 and ENSG00000109320 and 4790, transcription regulatory region DNA binding, nuclei, Nfkb1 and IDBG-195445 and ENSMUSG00000028163 and 18033, BT.60919 and IDBG-640840 and ENSBTAG00000020270 and 616115
  • Tissue
    cells
Gene info
Gene info
Gene info
  • Identity
    HGNC:7780
  • Gene
    NFE2
  • Long gene name
    nuclear factor, erythroid 2
  • Synonyms gene name
    • nuclear factor (erythroid-derived 2), 45kD
    • nuclear factor (erythroid-derived 2), 45kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q13.13
  • Discovery year
    1993-11-03
  • Entrez gene record
    4778
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Basic leucine zipper proteins
  • VEGA ID
    OTTHUMG00000169761
Gene info
Gene info
  • Identity
    HGNC:6057
  • Gene
    INA
  • Long gene name
    internexin neuronal intermediate filament protein alpha
  • Synonyms gene
  • Synonyms gene name
    • internexin neuronal intermediate filament protein, alpha
  • Synonyms
  • GenBank acession
  • Locus
    10q24.33
  • Discovery year
    1999-03-24
  • Entrez gene record
    9118
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Intermediate filaments Type IV
  • VEGA ID
    OTTHUMG00000018986
Gene info
Gene info
  • Identity
    HGNC:7775
  • Gene
    NFATC1
  • Long gene name
    nuclear factor of activated T cells 1
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
    • nuclear factor of activated T-cells 1
  • Synonyms
  • GenBank acession
  • Locus
    18q23
  • Discovery year
    1994-11-16
  • Entrez gene record
    4772
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Nuclear factors of activated T-cells
    • IPT domain containing
  • VEGA ID
    OTTHUMG00000132897
Gene info
  • Identity
    HGNC:7776
  • Gene
    NFATC2
  • Long gene name
    nuclear factor of activated T cells 2
  • Synonyms gene name
    • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
    • nuclear factor of activated T-cells 2
  • Synonyms
  • GenBank acession
  • Locus
    20q13.2
  • Discovery year
    1994-11-16
  • Entrez gene record
    4773
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • IPT domain containing
    • Nuclear factors of activated T-cells
    • MicroRNA protein coding host genes
  • VEGA ID
    OTTHUMG00000032747
Gene info
Gene info
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NFkB p50 GST delta434 969) (NF kB Factor kappa B p50 Subunit
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