α-naphthoflavone

• Catalog number
  2918-5
• Price
  Please ask
• Size
  5 g

• Alternative_name
  2-phenyl-4H-naphtho[1,2-b]pyran-4-one, NSC 407011, 7,8-Benzoflavone
• Description
  Potent and selective inhibitor of CYP19 (aromatase), CYP1A1, CYP1A2, and CYP1B1 (IC50 = 500, 60, 6, and 5 nM respectively). Can activate CYP3A4 (Kd = 7.4 µM).
• CAS Number
  604-59-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₂O₂
• Molecular Weight
  272.3
• Purity
  ≥98%
• Solubilities
  DMSO (~10 mg/ml) or DMF (~20 mg/ml), Ethanol (~1 mg/ml)
• Handling
  Protect from air, light and moisture
• Tag Line
  A potent inhibitor of Cytochrome P450 enzymes (Aromatase, 1A2, 1A1, 1B1)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00004985
• PubChem CID
  11790
• PubChem CID Link
• SMILES
  O=C1C2=C(C(C=CC=C3)=C3C=C2)OC(C4=CC=CC=C4)=C1
• InChi
  InChI=1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
• InChi Key
  VFMMPHCGEFXGIP-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  α-naphthoflavone  
• Short name
  α-naphthoflavone
• Alternative name
  α-naphthoflavone

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