AS-8351,KDM5B histone demethylase inhibitor

  • Catalog number
    SIH-558-25MG
  • Price
    Please ask
  • Size
    25 mg
  • Research Area s
    Stem Cells
  • Category
    Small Molecules
  • Product Type
    Inhibitor
  • CAS No
    796-42-9
  • MolecularFormula
    C17H13N3O2
  • Molecular Weight
    291.3
  • Purity
    >98% (TLC); NMR (Conforms)
  • Solubility
    May be dissolved in DMSO (45 mg/ml); or ethanol (10 mg/ml, warm); or DMF (30 mg/ml)
  • Appearance
    Yellow powder
  • Storage Temperature
    -20°C
  • Shipping Temperature
    Blue Ice or 4ºC
  • Description
    Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Gene target
  • Gene symbol
    KRT7-AS, DM1-AS, LRP1-AS, APOA1-AS, SIRT1-AS, ATXN2-AS, IRAIN, KDM5B, CTBP1-AS, HLA-B
  • Short name
    AS-8351 KDM5B histone demethylase inhibitor
  • Alternative name
    AS-8351,KDM5B histone demethylase suppressor
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    major histocompatibility complex, class I, B
  • Synonyms gene
  • Synonyms gene name
    • ankylosing spondylitis
  • GenBank acession
  • Locus
  • Discovery year
    2001-06-22
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • C1-set domain containing
    • Histocompatibility complex
    • MicroRNA protein coding host genes
  • VEGA ID
  • Locus Specific Databases
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