Anti-S1P1 Antibody

• Catalog number
  A1296-50
• Price
  Please ask
• Size
  50 µg

• Antibody Target
  S1PR1
• Target Alternative Name
  S1P Receptor 1, S1PR1, Sphingosine 1-Phosphate Receptor 1, Endothelial differentiation GProtein Coupled Receptor 1, EDG-1.
• Antibody Type
  Monoclonal
• Clone
  2B9
• Species Reactivities
  Human
• Immunogen Sequence
  Modified 5-hydroxymethylcytosine found in DNA vertebrates
• Accession
  P21453
• Gene Id
  1901
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  Phosphate Buffer 10mM - NaCl 0.15M - pH 7,4
• Purification
  Affinity purified
• Application
  ELISA, IP, IF, WB, FACS
• Positive Control
  WB: HUVEC cells, IP: CHO-S1P1-GFP cell membranes, IF: HUVEC cells
• Application And Usages
  ELISA: 1:4000 to 1:10000, IP: 1-300, IF: 1:500, WB; 1:5000, FACS; 1:100
• Description
  Sphingosine 1-Phosphate Receptor 1 (S1P1) is a multi-pass cell membrane protein that belongs to the Gprotein coupled receptor superfamily (GPCR). S1P1 is a receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Clinical significance of S1P1 encompasses various diseases including cancer and multiple sclerosis. S1P1 seems to be coupled to the G(i/o) subclass of heteromeric G proteins
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  S1P1  
• Short name
  Anti-S1P1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG2a
• Alternative name
  Antibody toS1P1 (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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