DOG-1/ ANO1 Antibody

• Catalog number
  GEN438470
• Price
  Please ask
• Size
  100ug

• Also known as
  DOG-1
• Other names
  anoctamin-1; Anoctamin-1; anoctamin-1; Ca2+-activated Cl- channel; oral cancer overexpressed 2; tumor-amplified and overexpressed sequence 2; discovered on gastrointestinal stromal tumors protein 1; transmembrane protein 16A (eight membrane-spanning domains); anoctamin 1, calcium activated chloride channel; Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  TMEM16A
• Gene name synonims
  N/A
• Other gene names
  ANO1; ANO1; DOG1; TAOS2; ORAOV2; TMEM16A; DOG1; ORAOV2; TAOS2; TMEM16A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa + IgG1, kappa
• Clone
  DG1/447 + DOG-1.1
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94.4% vs. 94.7%.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Canine or Canis Lupus is mostly Beagle used for drug research. MBS Monoclonals produces ELISA test kits and polyclonal antibodies.
• French translation
  anticorps

• Gene target
  ANO1  
• Gene symbol
  ANO1-AS1, LINC02584, ANO1
• Short name
  -1/ ANO1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Species
  Dog, Dogs
• Alternative name
  Anti-DOG-1/ ANO1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40016
• Gene
  ANO1-AS1
• Long gene name
  ANO1 antisense RNA 1
• Synonyms gene name
  • ANO1 antisense RNA 1 (non-protein coding)
• Locus
  11q13.3
• Discovery year
  2011-04-28
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167205

Gene info

• Identity
  HGNC:33275
• Gene
  LINC02584
• Long gene name
  long intergenic non-protein coding RNA 2584
• Synonyms gene
  • C11orf78
  • NCRNA00224
  • ANO1-AS2
• Synonyms gene name
  • chromosome 11 open reading frame 78
  • non-protein coding RNA 224
  • ANO1 antisense RNA 2 (non-protein coding)
  • ANO1 antisense RNA 2
  • ANO1 antisense RNA 2 (head to head)
• GenBank acession
  • AW592641
  • EF419887
• Locus
  11q13.3
• Discovery year
  2007-01-29
• Entrez gene record
  100009613
• RefSeq identity
  • NR_103835
• Classification
  • Long intergenic non-protein coding RNAs
• VEGA ID
  OTTHUMG00000167162

Gene info

• Identity
  HGNC:21625
• Gene
  ANO1
• Long gene name
  anoctamin 1
• Synonyms gene
  • ORAOV2
  • TMEM16A
• Synonyms gene name
  • oral cancer overexpressed 2
  • transmembrane protein 16A
  • anoctamin 1, calcium activated chloride channel
• Synonyms
  • TAOS2
  • FLJ10261
  • DOG1
• GenBank acession
  • BC033036
• Locus
  11q13.3
• Discovery year
  2003-10-16
• Entrez gene record
  55107
• Pubmed identfication
  • 15067359
  • 18724360
  • 24692353
• RefSeq identity
  • NM_018043
• Classification
  • Anoctamins
• VEGA ID
  OTTHUMG00000167204

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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