ACC2 Inhibitor
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Catalog number1717-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(1-(2’-(4-Isopropoxyphenoxy)-2,5’-bithiazol-5-yl)ethyl)acetamide
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DescriptionCell-permeable. A potent and selective inhibitor of ACC2 (Acetyl-CoA Carboxylase) (IC₅₀ = 28 nM for hACC2 vs 210 nM for hACC1 in in vitro studies).
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₉H₂₁N₃O₃S₂
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Molecular Weight403.52
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA selective inhibitor of ACC2
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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SMILESCC(C)OC(C=C1)=CC=C1OC2=NC=C(C(S3)=NC=C3C(C)NC(C)=O)S2
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InChiInChI=1S/C19H21N3O3S2/c1-11(2)24-14-5-7-15(8-6-14)25-19-21-10-17(27-19)18-20-9-16(26-18)12(3)22-13(4)23/h5-12H,1-4H3,(H,22,23)
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InChi KeyCVAJIWQTUPPAIF-UHFFFAOYSA-N
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MSDS AvailableYes
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Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolACACB, BCL2A1
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Short nameACC2 Inhibitor
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Alternative nameACC2 suppressor
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Gene info
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Identity
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Gene
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Long gene nameacetyl-CoA carboxylase beta
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Synonyms gene name
- acetyl-Coenzyme A carboxylase beta
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-12-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 related protein A1
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Synonyms gene
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Synonyms
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Locus
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Discovery year1995-05-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Minor histocompatibility antigens
- BCL2 family
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VEGA ID